Does Preoperative Transarterial Chemoembolization for Hepatocellular Carcinoma Increase the Incidence of Hepatic Artery Thrombosis After Living-Donor Liver Transplant?

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dc.authoridKARAKAS, SERDAR/0000-0001-8314-7806
dc.authoridYilmaz, Sezai/0000-0002-8044-0297
dc.authoridKaradag Soylu, Nese/0000-0002-6303-5484
dc.authoridKutluturk, Koray/0000-0002-7030-4953
dc.authoridince, volkan/0000-0002-0714-490X
dc.authoridKutlu, Ramazan/0000-0001-7941-7025
dc.authoridErsan, Veysel/0000-0002-1510-0288
dc.authorwosidKARAKAS, SERDAR/AAB-3219-2021
dc.authorwosidYilmaz, Sezai/ABI-2323-2020
dc.authorwosidKaradag Soylu, Nese/ABH-9544-2020
dc.authorwosidKutluturk, Koray/S-5493-2019
dc.authorwosidince, volkan/M-7325-2017
dc.authorwosidKutlu, Ramazan/AAE-5219-2020
dc.authorwosidErsan, Veysel/AAB-9595-2020
dc.contributor.authorInce, Volkan
dc.contributor.authorErsan, Veysel
dc.contributor.authorKarakas, Serdar
dc.contributor.authorKutluturk, Koray
dc.contributor.authorKaradag, Nese
dc.contributor.authorKutlu, Ramazan
dc.contributor.authorYilmaz, Sezai
dc.date.accessioned2024-08-04T20:43:03Z
dc.date.available2024-08-04T20:43:03Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjectives: Transarterial chemoembolization is a potential risk factor for hepatic artery damage, which may lead to severe consequences. We aimed to investigate this controversial issue in our population of liver transplant patients with hepatocellular carcinoma. Materials and Methods: Between March 2006 and December 2016, a total of 262 patients with hepa-tocellular carcinoma underwent liver transplant at our institution. Of these, 22 (8.4%) had preoperative transarterial chemoembolization. We retrospectively reviewed the data of all patients, comparing those who did and did not undergo transarterial chemo embolization. Results: The groups were similar in terms of patient sex, mean age, mean alpha-fetoprotein levels, and Milan criteria. The nontransarterial chemoembolization group had a significantly higher mean Model for End-Stage Liver Disease score. Hepatic artery thrombosis after liver transplantation was diagnosed in 6 of 22 patients (27%) in the transarterial chemoembolization group and in 12 of 240 patients (5%) in the non transarterial chemoembolization group (P = .002). Retransplant was performed in 5 of the 6 patients with hepatic artery thrombosis in the transarterial chemo embolization group and 3 of the 12 patients in the nontransarterial chemoembolization group (P = .04). Conclusions: In patients who undergo transarterial chemoembolization before liver transplantation, the incidence of hepatic artery thrombosis and retrans plantation is significantly higher than in those who do not undergo this intervention. The tissues should be carefully handled at the time of transplantation to prevent trauma that may cause intimal dissection in the fragile vessels.en_US
dc.identifier.doi10.6002/ect.TOND16.L7
dc.identifier.endpage24en_US
dc.identifier.issn1304-0855
dc.identifier.pmid28301994en_US
dc.identifier.scopus2-s2.0-85016429857en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage21en_US
dc.identifier.urihttps://doi.org/10.6002/ect.TOND16.L7
dc.identifier.urihttps://hdl.handle.net/11616/97765
dc.identifier.volume15en_US
dc.identifier.wosWOS:000399334300005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBaskent Univen_US
dc.relation.ispartofExperimental and Clinical Transplantationen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIntimal dissectionen_US
dc.subjectRetransplantationen_US
dc.titleDoes Preoperative Transarterial Chemoembolization for Hepatocellular Carcinoma Increase the Incidence of Hepatic Artery Thrombosis After Living-Donor Liver Transplant?en_US
dc.typeArticleen_US

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