P50 Sensory Gating Deficit in Obese Individuals

dc.authoridKamisli, Suat/0000-0003-4281-3301
dc.authoridTecellioglu, Mehmet/0000-0002-8381-9630
dc.authorwosidKamisli, Suat/AAC-2706-2021
dc.authorwosidKamisli, Suat/JZT-8388-2024
dc.authorwosidBentli, Recep/AAB-4140-2021
dc.authorwosidKamisli, Suat/JVN-4663-2024
dc.authorwosidTecellioglu, Mehmet/AAA-3220-2021
dc.contributor.authorTecellioglu, Mehmet
dc.contributor.authorBentli, Recep
dc.contributor.authorKamisli, Suat
dc.date.accessioned2024-08-04T20:09:47Z
dc.date.available2024-08-04T20:09:47Z
dc.date.issued2015
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Obesity may cause cognitive dysfunctions such as attention, processing speed, memory, and executive functioning. However, little is known about how obesity can affect cognitive functions in obese individuals. Sensory gating shows the early pre-attention period in information processing and is accepted to be the result of the integration of multi-step procedures that can be tested with the double click P50 paradigm. The aim of this study is to investigate changes in cognitive functions with sensory gating in obese individuals. Methods: A total of 31 obese individuals and age- and sex-matched healthy 24 control subjects were included in the study. The latencies and amplitude P50 waves were measured in the healthy controls and obese individuals. Also the P50 sensory gating was calculated. Results: We found a significant difference between the obese group and controls regarding the amplitude of the first P50 wave (p<0.048). The obese group showed reduced P50 sensory gating as compared to controls (p<0.004). Conclusion: The findings suggest that obese individuals have a sensory gating abnormality seems to be a result of cholinergic dysfunction. This results may help explain congnitive impairment in obese individuals.en_US
dc.identifier.doi10.12996/gmj.2015.30
dc.identifier.endpage100en_US
dc.identifier.issn2147-2092
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84936863588en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage97en_US
dc.identifier.trdizinid212367en_US
dc.identifier.urihttps://doi.org/10.12996/gmj.2015.30
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/212367
dc.identifier.urihttps://hdl.handle.net/11616/92441
dc.identifier.volume26en_US
dc.identifier.wosWOS:000217477300006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherGazi Univ, Fac Meden_US
dc.relation.ispartofGazi Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectObesityen_US
dc.subjectsensory gatingen_US
dc.subjectcholinergic dysfunctionen_US
dc.subjectcognitionen_US
dc.titleP50 Sensory Gating Deficit in Obese Individualsen_US
dc.typeArticleen_US

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