Effects of reciprocal interactions between various dietary fats and circadian phases on postprandial hyperlipidemia in rats
Yükleniyor...
Dosyalar
Tarih
2017
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Biological Rhythm Research
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Expression levels of various intestinal proteins involved in postprandial
lipoprotein assembly as well as plasma triglyceride concentration
exhibit daily oscillations indicating circadian control. The length of the
carbon chain and degree and position of unsaturation of fatty acids
influence triglyceride secretion by the enterocytes. To this end, effects
of reciprocal interactions of various single fats/oil (olive oil, fish oil or
butter) gavaging either in active or passive phase were investigated in
rats. Fat/oil gavaged in the active phase of circadian rhythm resulted
in higher postprandial serum triglyceride levels compared to that
in the passive phase. Moreover, olive oil led to higher MTP activity
and apo B-48 gene expression, while fish oil gavaging caused more
prominent apo B-48 and MTP gene expression when they were given
in the passive phase. The present results indicate that circadian time at
which fat or oil gavaged once might exert influence on postprandial
lipoprotein synthesis/assembly.
Açıklama
Anahtar Kelimeler
Circadian rhythms, Dietary fats, Chylomicron, Hyperlipidemia, Microsomal triglyceride transfer protein
Kaynak
Biological Rhythm Research
WoS Q Değeri
Scopus Q Değeri
Cilt
Sayı
Künye
Satılmış, B. Kayhan, B. Güldür, T. (2017). Effects of reciprocal interactions between various dietary fats and circadian phases on postprandial hyperlipidemia in rats. Biological Rhythm Research, 1–15.
