Effects of reciprocal interactions between various dietary fats and circadian phases on postprandial hyperlipidemia in rats

dc.authorid41809en_US
dc.contributor.authorSatılmış, Basri
dc.contributor.authorKayhan, Başak
dc.contributor.authorGüldür, Tayfun
dc.date.accessioned2017-08-01T05:34:44Z
dc.date.available2017-08-01T05:34:44Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractExpression levels of various intestinal proteins involved in postprandial lipoprotein assembly as well as plasma triglyceride concentration exhibit daily oscillations indicating circadian control. The length of the carbon chain and degree and position of unsaturation of fatty acids influence triglyceride secretion by the enterocytes. To this end, effects of reciprocal interactions of various single fats/oil (olive oil, fish oil or butter) gavaging either in active or passive phase were investigated in rats. Fat/oil gavaged in the active phase of circadian rhythm resulted in higher postprandial serum triglyceride levels compared to that in the passive phase. Moreover, olive oil led to higher MTP activity and apo B-48 gene expression, while fish oil gavaging caused more prominent apo B-48 and MTP gene expression when they were given in the passive phase. The present results indicate that circadian time at which fat or oil gavaged once might exert influence on postprandial lipoprotein synthesis/assembly.en_US
dc.identifier.citationSatılmış, B. Kayhan, B. Güldür, T. (2017). Effects of reciprocal interactions between various dietary fats and circadian phases on postprandial hyperlipidemia in rats. Biological Rhythm Research, 1–15.en_US
dc.identifier.doi10.1080/09291016.2017.1333199en_US
dc.identifier.endpage15en_US
dc.identifier.issn0929-1016
dc.identifier.startpage1en_US
dc.identifier.urihttps://www.tandfonline.com/doi/full/10.1080/09291016.2017.1333199
dc.identifier.urihttps://hdl.handle.net/11616/7418
dc.language.isoenen_US
dc.publisherBiological Rhythm Researchen_US
dc.relation.ispartofBiological Rhythm Researchen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCircadian rhythmsen_US
dc.subjectDietary fatsen_US
dc.subjectChylomicronen_US
dc.subjectHyperlipidemiaen_US
dc.subjectMicrosomal triglyceride transfer proteinen_US
dc.titleEffects of reciprocal interactions between various dietary fats and circadian phases on postprandial hyperlipidemia in ratsen_US
dc.typeArticleen_US

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