Albendazole induced recurrent acute toxic hepatitis: A case report
Küçük Resim Yok
Tarih
2017
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Universa Press
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Introduction: Drug induced acute toxic hepatitis can be idiosyncratic. Albendazole, a widely used broad spectrum antiparasitic drug is generally accepted as a safe drug. It may cause asymptomatic transient liver enzyme abnormalities but acute toxic hepatitis is very rare. Case Report: Herein, we present the case of 47 year old woman with recurrent acute toxic hepatitis after a single intake of albendazole in 2010 and 2014. The patient was presented with symptoms and findings of anorexia, vomiting and jaundice. For diagnosis, other acute hepatitis etiologies were excluded. Roussel Uclaf Causality Assessment Method (RUCAM) score was calculated and found to be 10, which meant highly probable drug hepatotoxicity. Within 2 months, all pathological findings came to normal. Result: There are a few reported cases of albendazole induced toxic hepatitis, but at adults, there is no known recurrent acute toxic hepatitis due to albendazole at this certainty according to RUCAM score. Conclusion: Physicians should be aware of this rare and potentially fatal adverse effect of albendazole. © 2017, Universa Press. All rights reserved.
Açıklama
Anahtar Kelimeler
Albendazole, Hepatitis, Recurrent, Toxic
Kaynak
Acta Gastro-Enterologica Belgica
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
80
Sayı
2
