Albendazole induced recurrent acute toxic hepatitis: A case report

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dc.authorscopusid23979648200
dc.authorscopusid57214577978
dc.authorscopusid58346789400
dc.authorscopusid36112747100
dc.authorscopusid23018615700
dc.authorscopusid55396465200
dc.contributor.authorBilgic Y.
dc.contributor.authorYilmaz C.
dc.contributor.authorCagin Y.F.
dc.contributor.authorAtayan Y.
dc.contributor.authorKaradag N.
dc.contributor.authorHarputluoglu M.M.M.
dc.date.accessioned2024-08-04T20:02:35Z
dc.date.available2024-08-04T20:02:35Z
dc.date.issued2017
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: Drug induced acute toxic hepatitis can be idiosyncratic. Albendazole, a widely used broad spectrum antiparasitic drug is generally accepted as a safe drug. It may cause asymptomatic transient liver enzyme abnormalities but acute toxic hepatitis is very rare. Case Report: Herein, we present the case of 47 year old woman with recurrent acute toxic hepatitis after a single intake of albendazole in 2010 and 2014. The patient was presented with symptoms and findings of anorexia, vomiting and jaundice. For diagnosis, other acute hepatitis etiologies were excluded. Roussel Uclaf Causality Assessment Method (RUCAM) score was calculated and found to be 10, which meant highly probable drug hepatotoxicity. Within 2 months, all pathological findings came to normal. Result: There are a few reported cases of albendazole induced toxic hepatitis, but at adults, there is no known recurrent acute toxic hepatitis due to albendazole at this certainty according to RUCAM score. Conclusion: Physicians should be aware of this rare and potentially fatal adverse effect of albendazole. © 2017, Universa Press. All rights reserved.en_US
dc.identifier.endpage311en_US
dc.identifier.issn1784-3227
dc.identifier.issue2en_US
dc.identifier.pmid29560698en_US
dc.identifier.scopus2-s2.0-85028467641en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage309en_US
dc.identifier.urihttps://hdl.handle.net/11616/91805
dc.identifier.volume80en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherUniversa Pressen_US
dc.relation.ispartofActa Gastro-Enterologica Belgicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAlbendazoleen_US
dc.subjectHepatitisen_US
dc.subjectRecurrenten_US
dc.subjectToxicen_US
dc.titleAlbendazole induced recurrent acute toxic hepatitis: A case reporten_US
dc.typeArticleen_US

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