Comparison of itraconazole and terbinafine in the treatment of superficial dermatophyte infections
Küçük Resim Yok
Tarih
1995
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background and design. - In recent years, itraconazole and terbinafine have been widely used in the treatment of superficial fungal diseases. In this study, we aimed to compare the efficacy and side effects of these 2 agents. Seventy eight patients with superficial dermatophyte infection, were given either itraconazol (100 mg/d) or terbinafine (250 mg/d) for two weeks. The efficacy of the treatment was evaluated by KOH examination at 30th, 60th and 90th day after cessation of the drug. Side effect profile was decided with patients' complaints and laboratory examinations. Results. - At the end of the study 30 of 39 patients in the itraconazole group and 31 of 39 patients in the terbinafine group, completed the study. There was no statistical difference between the two treatment groups regarding the efficacy of the treatment. Conclusion. - None of the patients described any subjective side effects and all laboratory examination results were either negative or normal. Itraconazole and terbinafine were found to be equally effective in superficial dermatophyte infections.
Açıklama
Anahtar Kelimeler
Dermatophytosis, Itraconazole, Terbinafine
Kaynak
Turkderm Deri Hastaliklari ve Frengi Arsivi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
29
Sayı
3-4
