Effect of the preservation-to-surgery interval on corneal allograft survival in low-risk patients

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dc.authoridYologlu, Saim/0000-0002-9619-3462
dc.authorwosidYologlu, Saim/ABI-8014-2020
dc.contributor.authorDoganay, Selim
dc.contributor.authorHepsen, I. Fevzi
dc.contributor.authorYologlu, Saim
dc.contributor.authorDemirtas, Hakan
dc.date.accessioned2024-08-04T20:30:39Z
dc.date.available2024-08-04T20:30:39Z
dc.date.issued2007
dc.departmentİnönü Üniversitesien_US
dc.descriptionAnnual Meeting of the American-Society-of-Cataract-and-Refractive-Surgery -- APR, 2005 -- Washington, DCen_US
dc.description.abstractm BACKGROUND AND OBJECTIVE: To investigate the role of the preservation-to-surgery interval on corneal allograft survival in low-risk patients. PATIENTS AND METHODS: Eighteen donor corneas obtained from an overseas eye bank were preserved and transported overseas in Optisol-GS solution (Chiron Vision, Irvine, CA) in Group 1. Thirty fresh, young, healthy, and unscreened donor corneas soaked in the same medium were used in Group 2. Average preservation-to-surgery time was more than 8 days in Group 1 and less than 30 hours in Group 2. Corneal allograft survival rates were determined by Kaplan-Meier estimates of the survivor functions. The log-rank test was used to determine statistical significance of the differences between groups. RESULTS: The mean preservation-to-surgery interval was 233.3 +/- 37.7 hours in Group I and 20.8 +/- 4.6 hours in Group 2 (P <.05 for the comparison of average times). There were significant differences between the groups with respect to donors' age and enucleation time, but there were no statistically significant differences between the groups in terms of graft diameter and recipient diameter or for corneal allograft survival in low-risk patients. The graft survival rate was 83.3% in Group I and 93.3% in Group 2 at the end of the follow-up period. CONCLUSIONS: Preservation-to-surgery time has no effect on corneal allograft survival in low-risk patients. However, prospective, randomized, long-term and large-scale clinical trials are necessary to confirm these findings.en_US
dc.description.sponsorshipAmer Soc Cataract & Refract Surgen_US
dc.identifier.doi10.3928/15428877-20071101-03
dc.identifier.endpage461en_US
dc.identifier.issn1542-8877
dc.identifier.issue6en_US
dc.identifier.pmid18050807en_US
dc.identifier.scopus2-s2.0-38349018636en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage457en_US
dc.identifier.urihttps://doi.org/10.3928/15428877-20071101-03
dc.identifier.urihttps://hdl.handle.net/11616/94429
dc.identifier.volume38en_US
dc.identifier.wosWOS:000250994700003en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSlack Incen_US
dc.relation.ispartofOphthalmic Surgery Lasers & Imagingen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectOrgan-Culture Mediumen_US
dc.subjectLangerhans Cellsen_US
dc.subjectDendritic Cellsen_US
dc.subjectStorage Timeen_US
dc.subjectDonoren_US
dc.subjectRejectionen_US
dc.subjectTransplantationen_US
dc.subjectTissueen_US
dc.titleEffect of the preservation-to-surgery interval on corneal allograft survival in low-risk patientsen_US
dc.typeConference Objecten_US

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