Trabeculectomy with brief exposure of mitomycin-C
Küçük Resim Yok
Tarih
1996
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, mitomycin-C (MMC) at a concentration of 0.2 mg/mL was applied intraoperatively for 1 minute in 11 consecutive primary trabeculectomies to increase the success of glaucoma-filtration surgery while minimizing the incidence of postoperative complications resulting from MMC use. The success criteria included a postoperative intraocular pressure (IOP) lower than 21 mmHg without treatment, a 20% or more drop from preoperative IOP levels, and a visual loss limited to one or fewer lines of Snellen acuity. The procedure was considered successful in 10 eyes (90.9%), with a mean follow-up period of 25.6 weeks. Blebs were ischemic and microcystic in all successful eyes at the time of the last follow up. Postoperative complications included subconjunctival hemorrhage, hyphema, conjunctival wound leak, and corneal epithelial defects. Complications related to low IOP, such as choroidal detachment and hypotonic maculopathy, were not seen in any of the eyes. Although the longer term of follow-up results of this regimen are not well known, this alternative intraoperative application of MMC at a concentration of 0.2 mg/mL for 1 minute seems to control postoperative IOP effectively in primary trabeculectomies with fewer hypotony-related complications.
Açıklama
Anahtar Kelimeler
antibiotic agent, atropine, beta adrenergic receptor blocking agent, corticosteroid, mitomycin c, adult, aged, article, child, clinical article, conjunctiva disease, cornea disease, female, filtering operation, glaucoma, human, hyphema, intraocular pressure, intraoperative period, male, postoperative complication, priority journal, topical drug administration, trabeculectomy, visual acuity, wound dehiscence
Kaynak
Annals of Ophthalmology - Glaucoma
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
28
Sayı
2