Trabeculectomy with brief exposure of mitomycin-C

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dc.authorscopusid6701335627
dc.authorscopusid6701587135
dc.authorscopusid6602578049
dc.contributor.authorHepşen I.F.
dc.contributor.authorBayramlar H.
dc.contributor.authorOram O.
dc.date.accessioned2024-08-04T20:00:46Z
dc.date.available2024-08-04T20:00:46Z
dc.date.issued1996
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIn this study, mitomycin-C (MMC) at a concentration of 0.2 mg/mL was applied intraoperatively for 1 minute in 11 consecutive primary trabeculectomies to increase the success of glaucoma-filtration surgery while minimizing the incidence of postoperative complications resulting from MMC use. The success criteria included a postoperative intraocular pressure (IOP) lower than 21 mmHg without treatment, a 20% or more drop from preoperative IOP levels, and a visual loss limited to one or fewer lines of Snellen acuity. The procedure was considered successful in 10 eyes (90.9%), with a mean follow-up period of 25.6 weeks. Blebs were ischemic and microcystic in all successful eyes at the time of the last follow up. Postoperative complications included subconjunctival hemorrhage, hyphema, conjunctival wound leak, and corneal epithelial defects. Complications related to low IOP, such as choroidal detachment and hypotonic maculopathy, were not seen in any of the eyes. Although the longer term of follow-up results of this regimen are not well known, this alternative intraoperative application of MMC at a concentration of 0.2 mg/mL for 1 minute seems to control postoperative IOP effectively in primary trabeculectomies with fewer hypotony-related complications.en_US
dc.identifier.endpage83en_US
dc.identifier.issn1079-4794
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-0029928840en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage80en_US
dc.identifier.urihttps://hdl.handle.net/11616/90992
dc.identifier.volume28en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofAnnals of Ophthalmology - Glaucomaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectantibiotic agenten_US
dc.subjectatropineen_US
dc.subjectbeta adrenergic receptor blocking agenten_US
dc.subjectcorticosteroiden_US
dc.subjectmitomycin cen_US
dc.subjectadulten_US
dc.subjectageden_US
dc.subjectarticleen_US
dc.subjectchilden_US
dc.subjectclinical articleen_US
dc.subjectconjunctiva diseaseen_US
dc.subjectcornea diseaseen_US
dc.subjectfemaleen_US
dc.subjectfiltering operationen_US
dc.subjectglaucomaen_US
dc.subjecthumanen_US
dc.subjecthyphemaen_US
dc.subjectintraocular pressureen_US
dc.subjectintraoperative perioden_US
dc.subjectmaleen_US
dc.subjectpostoperative complicationen_US
dc.subjectpriority journalen_US
dc.subjecttopical drug administrationen_US
dc.subjecttrabeculectomyen_US
dc.subjectvisual acuityen_US
dc.subjectwound dehiscenceen_US
dc.titleTrabeculectomy with brief exposure of mitomycin-Cen_US
dc.typeArticleen_US

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