The isolation rate and antibiotic resistant pattern of Helicobacter pylori in dyspeptic patients
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Dosyalar
Tarih
2000
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkish Journal of Medical Sciences
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Öz: In order to determine the isolation rates of Helicobacter pylori in dyspeptic patients, 167 biopsy specimens were examined using different methods, including culturing, microscopy and the rapid urease test. Resistance to commonly used antimicrobials was investigated using the disk diffusion method. Of the 167 specimens, 82(49.1%) were found to be positive for Helicobacter pylori in culture and 72(43 %) were positive in the urease biopsy test. Using Gram staining, Helicobacter pylori were observed in 43 (25.7 %) of the specimens. The resistance rate of the isolates was 53 % for metronidazol, 8% for both clarithromycin and ciprofloxacin, and 4% for tetracyline. The rate of resistance for amoxycillin was not recorded. Our results indicate that a susceptibility test is necessary before initiating therapy for Helicobacter pyloriinfections, otherwise treatment may be ineffective.
Abstract: In order to determine the isolation rates of Helicobacter pylori in dyspeptic patients, 167 biopsy specimens were examined using different methods, including culturing, microscopy and the rapid urease test. Resistance to commonly used antimicrobials was investigated using the disk diffusion method. Of the 167 specimens, 82(49.1%) were found to be positive for Helicobacter pylori in culture and 72(43 %) were positive in the urease biopsy test. Using Gram staining, Helicobacter pylori were observed in 43 (25.7 %) of the specimens. The resistance rate of the isolates was 53 % for metronidazol, 8% for both clarithromycin and ciprofloxacin, and 4% for tetracyline. The rate of resistance for amoxycillin was not recorded. Our results indicate that a susceptibility test is necessary before initiating therapy for Helicobacter pyloriinfections, otherwise treatment may be ineffective.
Abstract: In order to determine the isolation rates of Helicobacter pylori in dyspeptic patients, 167 biopsy specimens were examined using different methods, including culturing, microscopy and the rapid urease test. Resistance to commonly used antimicrobials was investigated using the disk diffusion method. Of the 167 specimens, 82(49.1%) were found to be positive for Helicobacter pylori in culture and 72(43 %) were positive in the urease biopsy test. Using Gram staining, Helicobacter pylori were observed in 43 (25.7 %) of the specimens. The resistance rate of the isolates was 53 % for metronidazol, 8% for both clarithromycin and ciprofloxacin, and 4% for tetracyline. The rate of resistance for amoxycillin was not recorded. Our results indicate that a susceptibility test is necessary before initiating therapy for Helicobacter pyloriinfections, otherwise treatment may be ineffective.
Açıklama
Yıl: 2000Cilt: 30Sayı: 2ISSN: 1300-0144 / 1303-6165Sayfa Aralığı: 143 - 146Metin Dili:İngilizce
Anahtar Kelimeler
Kaynak
Turkish Journal of Medical Sciences
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
30
Sayı
2
Künye
AĞEL E,DURMAZ B,TEVFİK M. R,AŞGIN N (2000). The isolation rate and antibiotic resistant pattern of Helicobacter pylori in dyspeptic patients. Turkish Journal of Medical Sciences, 30(2), 143 - 146.
