Synthesis of N-heterocyclic carbene-based silver complexes and their antimicrobial properties against bacteria and fungi

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dc.authoridGünal, Selami/0000-0002-4752-5176
dc.authoridKaloğlu, Murat/0000-0002-2770-5532
dc.authoridOzdemir, Ismail/0000-0001-6325-0216
dc.authorwosidGünal, Selami/AAA-7246-2021
dc.authorwosidKaloğlu, Murat/AAA-3956-2021
dc.contributor.authorKaloglu, Murat
dc.contributor.authorKaloglu, Nazan
dc.contributor.authorGunal, Selami
dc.contributor.authorOzdemir, Ismail
dc.date.accessioned2024-08-04T20:50:55Z
dc.date.available2024-08-04T20:50:55Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractN-Heterocyclic carbene-based silver complexes (Ag-NHCs) have been widely used as organometallic drug candidates in medicinal and pharmaceutical chemistry research due to their low toxicity. Due to the success of Ag-NHCs in biological applications, interest in the synthesis and applications of such compounds is increasing rapidly. Therefore, in this study, ten Ag-NHC complexes containing benzimidazol-2-ylidene ligand were synthesized and characterized by H-1 NMR, C-13 NMR, FT-IR spectroscopies and elemental analyses. The antimicrobial activity of Ag-NHCs was tested against some standard culture collections of Gram-negative, Gram-positive bacterial strains and fungal strains, which are the most frequently isolated among the society and hospital acquired infectious microorganisms as potential metallopharmaceutical agents. The Ag-NHC complexes showed effective antimicrobial activity against microorganisms with MIC values between 6.25 and 100 mu g/mL.en_US
dc.identifier.doi10.1080/00958972.2021.2014457
dc.identifier.endpage3047en_US
dc.identifier.issn0095-8972
dc.identifier.issn1029-0389
dc.identifier.issue17-20en_US
dc.identifier.scopus2-s2.0-85121373547en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage3031en_US
dc.identifier.urihttps://doi.org/10.1080/00958972.2021.2014457
dc.identifier.urihttps://hdl.handle.net/11616/100368
dc.identifier.volume74en_US
dc.identifier.wosWOS:000729091200001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofJournal of Coordination Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectN-Heterocyclic carbeneen_US
dc.subjectbenzimidazol-2-ylideneen_US
dc.subjectsilveren_US
dc.subjectantimicrobial activityen_US
dc.subjectmetallodrugsen_US
dc.titleSynthesis of N-heterocyclic carbene-based silver complexes and their antimicrobial properties against bacteria and fungien_US
dc.typeArticleen_US

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