Lymphocyte-to-C-reactive protein ratio as a new biomarker for predicting mortality and morbidity in Fournier's gangrene
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Permanyer Publications
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: The purpose of this study was to research the neutrophil-lymphocyte ratio (NLR), lymphocyte-to-C-reactive protein ratio (LCR), and Fournier's Gangrene Severity Index (FGSI) for predicting prognosis and mortality in patients with Fournier's gangrene (FG). Material and Methods: Patients diagnosed with FG and treated in a tertiary referral hospital in the period from January 2013 to June 2020 were reviewed. LCR, FGSI, and NLR values were calculated. Results: Our series included a total of 41 patients. Of the patients, 78% survived and 21.9% (n = 9) died. Survivors were significantly younger than non-survivors (p = 0.009). Hospital costs were higher in non-survivors and close to statistical significance (p = 0.08). The ROC analysis revealed that the FGSI, LCR, and NLR parameters were significant in identifying survivors and non-survivors (AUC = 0.941 [0.870-1.000], p < 0.001; AUC = 0.747 [0.593-0.900], p = 0.025; and AUC = 0.724 [0.548-0.900], p = 0.042). Conclusion: A low LCR value can be used as a marker to assess mortality and disease severity in patients with Fournier's gangrene. © 2024 Permanyer Publications. All rights reserved.
Açıklama
Anahtar Kelimeler
Cost effective, Fournier's gangrene, Lymphocyte C-reactive protein ratio, Mortality
Kaynak
Cirugia y Cirujanos (English Edition)
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
92
Sayı
2
