Lymphocyte-to-C-reactive protein ratio as a new biomarker for predicting mortality and morbidity in Fournier's gangrene

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dc.authorscopusid57217367304
dc.authorscopusid59142987000
dc.authorscopusid57223192724
dc.authorscopusid57222958312
dc.authorscopusid57222960810
dc.authorscopusid56496798000
dc.authorscopusid7003509999
dc.contributor.authorYildirim M.
dc.contributor.authorGul S.C.
dc.contributor.authorAngin Y.S.
dc.contributor.authorSaglam A.I.
dc.contributor.authorOzsoy U.
dc.contributor.authorKoca B.
dc.contributor.authorOzkan N.
dc.date.accessioned2024-08-04T19:59:05Z
dc.date.available2024-08-04T19:59:05Z
dc.date.issued2024
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The purpose of this study was to research the neutrophil-lymphocyte ratio (NLR), lymphocyte-to-C-reactive protein ratio (LCR), and Fournier's Gangrene Severity Index (FGSI) for predicting prognosis and mortality in patients with Fournier's gangrene (FG). Material and Methods: Patients diagnosed with FG and treated in a tertiary referral hospital in the period from January 2013 to June 2020 were reviewed. LCR, FGSI, and NLR values were calculated. Results: Our series included a total of 41 patients. Of the patients, 78% survived and 21.9% (n = 9) died. Survivors were significantly younger than non-survivors (p = 0.009). Hospital costs were higher in non-survivors and close to statistical significance (p = 0.08). The ROC analysis revealed that the FGSI, LCR, and NLR parameters were significant in identifying survivors and non-survivors (AUC = 0.941 [0.870-1.000], p < 0.001; AUC = 0.747 [0.593-0.900], p = 0.025; and AUC = 0.724 [0.548-0.900], p = 0.042). Conclusion: A low LCR value can be used as a marker to assess mortality and disease severity in patients with Fournier's gangrene. © 2024 Permanyer Publications. All rights reserved.en_US
dc.identifier.doi10.24875/CIRU.22000529
dc.identifier.endpage188en_US
dc.identifier.issn0009-7411
dc.identifier.issue2en_US
dc.identifier.pmid38782374en_US
dc.identifier.scopus2-s2.0-85194130542en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage181en_US
dc.identifier.urihttps://doi.org/10.24875/CIRU.22000529
dc.identifier.urihttps://hdl.handle.net/11616/90369
dc.identifier.volume92en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherPermanyer Publicationsen_US
dc.relation.ispartofCirugia y Cirujanos (English Edition)en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCost effectiveen_US
dc.subjectFournier's gangreneen_US
dc.subjectLymphocyte C-reactive protein ratioen_US
dc.subjectMortalityen_US
dc.titleLymphocyte-to-C-reactive protein ratio as a new biomarker for predicting mortality and morbidity in Fournier's gangreneen_US
dc.typeArticleen_US

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