The beneficial effect of melatonin on chronic cyclosporin A nephrotoxicity in rats

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dc.authoridEşrefoğlu, Mukaddes/0000-0003-3380-1480
dc.authorwosidEşrefoğlu, Mukaddes/JWA-4590-2024
dc.contributor.authorEsrefoglu, M
dc.contributor.authorKurus, M
dc.contributor.authorSahna, E
dc.date.accessioned2024-08-04T20:13:36Z
dc.date.available2024-08-04T20:13:36Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractCyclosporin A (CsA)-induced nephrotoxicity may be the consequence of oxidative stress. Anti-oxidant agents could be useful in reducing CsA toxicity. In this light microscopy study, tubular dilatation, atrophy, vacuolization and tubulointerstitial fibrosis were observed in rats given CsA, whereas in rats given CsA plus melatonin, no histological changes occurred. It is concluded that melatonin could be useful for reducing the nephrotoxic effects of CsA.en_US
dc.identifier.endpage44en_US
dc.identifier.issn0300-0605
dc.identifier.issue1en_US
dc.identifier.pmid12635533en_US
dc.identifier.scopus2-s2.0-0348047623en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage42en_US
dc.identifier.urihttps://hdl.handle.net/11616/93724
dc.identifier.volume31en_US
dc.identifier.wosWOS:000181291300007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCambridge Med Publen_US
dc.relation.ispartofJournal of International Medical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcyclosporin Aen_US
dc.subjectmelatoninen_US
dc.subjectanti-oxidanten_US
dc.subjectnephrotoxicityen_US
dc.subjectraten_US
dc.subjectlight microscopyen_US
dc.subjecttubulointerstitial fibrosisen_US
dc.subjecttubular atrophyen_US
dc.titleThe beneficial effect of melatonin on chronic cyclosporin A nephrotoxicity in ratsen_US
dc.typeArticleen_US

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