A multicentric, hyaline vascular variant of Castleman's disease associated with B cell lymphoma: A case report
Küçük Resim Yok
Tarih
2009
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Introduction: Three histological variants (hyaline vascular, plasma cell, and mixed) and two clinical types (localized and multicentric) of Castleman's disease have been described. The risk of progression to lymphoma is higher in multicentric Castleman's disease and is associated with poorer outcomes and higher mortality rate. Multicentric Castleman's disease often requires systemic therapy. Complete resection of the involved node in localized Castleman's disease is curative, with no reported recurrences. Case presentation: We report a case of a 66-year-old female with systemic symptoms and bilateral cervical lymph nodes which were initially diagnosed as the hyaline vascular variant of Castleman's disease and two years later after the initial diagnosis she was confirmed to B cell lymphoma. Following the treatment with radiation therapy to the cervical area and combination chemotherapy complete response was achieved. Conclusion: Although it has rarely been reported, the malignant potential of the Castleman's disease must be kept in mind. © 2009 Erkurt et al; licensee Cases Network Ltd.
Açıklama
Anahtar Kelimeler
CD19 antigen, CD20 antigen, CD22 antigen, CD3 antigen, CD30 antigen, CD4 antigen, CD45 antigen, CD5 antigen, CD8 antigen, CD99 antigen, common acute lymphoblastic leukemia antigen, cyclophosphamide, doxorubicin, prednisone, vincristine, abdominal radiography, aged, angiofollicular lymph node hyperplasia, article, B cell lymphoma, cancer combination chemotherapy, cancer radiotherapy, case report, case study, cervical lymph node, dyspnea, female, follow up, histopathology, human, lymph node biopsy, lymph node hyperplasia, lymphadenopathy, pain, physical examination, treatment response
Kaynak
Cases Journal
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
2
Sayı
6
