A multicentric, hyaline vascular variant of Castleman's disease associated with B cell lymphoma: A case report

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dc.authorscopusid8842895600
dc.authorscopusid56264100700
dc.authorscopusid6603472555
dc.authorscopusid7004568106
dc.authorscopusid56108998400
dc.authorscopusid26038995800
dc.contributor.authorErkurt M.A.
dc.contributor.authorAydogdu I.
dc.contributor.authorKuku I.
dc.contributor.authorKaya E.
dc.contributor.authorMizrak B.
dc.contributor.authorBasaran Y.
dc.date.accessioned2024-08-04T20:02:34Z
dc.date.available2024-08-04T20:02:34Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description.abstractIntroduction: Three histological variants (hyaline vascular, plasma cell, and mixed) and two clinical types (localized and multicentric) of Castleman's disease have been described. The risk of progression to lymphoma is higher in multicentric Castleman's disease and is associated with poorer outcomes and higher mortality rate. Multicentric Castleman's disease often requires systemic therapy. Complete resection of the involved node in localized Castleman's disease is curative, with no reported recurrences. Case presentation: We report a case of a 66-year-old female with systemic symptoms and bilateral cervical lymph nodes which were initially diagnosed as the hyaline vascular variant of Castleman's disease and two years later after the initial diagnosis she was confirmed to B cell lymphoma. Following the treatment with radiation therapy to the cervical area and combination chemotherapy complete response was achieved. Conclusion: Although it has rarely been reported, the malignant potential of the Castleman's disease must be kept in mind. © 2009 Erkurt et al; licensee Cases Network Ltd.en_US
dc.identifier.doi10.4076/1757-1626-2-8183
dc.identifier.issn1757-1626
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-77953391199en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.urihttps://doi.org/10.4076/1757-1626-2-8183
dc.identifier.urihttps://hdl.handle.net/11616/91799
dc.identifier.volume2en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.relation.ispartofCases Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCD19 antigenen_US
dc.subjectCD20 antigenen_US
dc.subjectCD22 antigenen_US
dc.subjectCD3 antigenen_US
dc.subjectCD30 antigenen_US
dc.subjectCD4 antigenen_US
dc.subjectCD45 antigenen_US
dc.subjectCD5 antigenen_US
dc.subjectCD8 antigenen_US
dc.subjectCD99 antigenen_US
dc.subjectcommon acute lymphoblastic leukemia antigenen_US
dc.subjectcyclophosphamideen_US
dc.subjectdoxorubicinen_US
dc.subjectprednisoneen_US
dc.subjectvincristineen_US
dc.subjectabdominal radiographyen_US
dc.subjectageden_US
dc.subjectangiofollicular lymph node hyperplasiaen_US
dc.subjectarticleen_US
dc.subjectB cell lymphomaen_US
dc.subjectcancer combination chemotherapyen_US
dc.subjectcancer radiotherapyen_US
dc.subjectcase reporten_US
dc.subjectcase studyen_US
dc.subjectcervical lymph nodeen_US
dc.subjectdyspneaen_US
dc.subjectfemaleen_US
dc.subjectfollow upen_US
dc.subjecthistopathologyen_US
dc.subjecthumanen_US
dc.subjectlymph node biopsyen_US
dc.subjectlymph node hyperplasiaen_US
dc.subjectlymphadenopathyen_US
dc.subjectpainen_US
dc.subjectphysical examinationen_US
dc.subjecttreatment responseen_US
dc.titleA multicentric, hyaline vascular variant of Castleman's disease associated with B cell lymphoma: A case reporten_US
dc.typeArticleen_US

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