Distribution of peripheral blood cells after splenectomy in immune thrombocytopenia patients
Küçük Resim Yok
Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Mexican Acad Surgery
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Background: There are some difficulties regarding the evaluation of the post-splenectomy state. Objective: The objective of the study is to compare the post-splenectomy blood changes of immune thrombocytopenia (ITP) patients with those of trauma patients, 1 month and >_ 6 months after surgery. Methods: Medical records of patients, who had undergone total splenectomy for ITP and trauma at a tertiary center between January 2009 and December 2019, were retrospectively reviewed. Results: The current study included 52 patients, who had undergone splenectomy for ITP (57.7%), and trauma (42.3%). Splenectomy, irrespective of the indications, resulted in an increase in hemoglobin concentration, hematocrit, and platelet levels. Neutrophils were responsible for the preoperative leukocytosis in ITP patients, and neutrophilia was ameliorated by splenectomy and also withdrawal of the steroid therapy in some patients. Decreased neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio supported the finding that splenectomy ameliorated inflammation in ITP patients. Splenectomy resulted in a change in percentages of leukocytes in favor of basophils in ITP patients. Conclusions: Splenectomy, irrespective of the indications, resulted in an increase in hemoglobin concentration, hematocrit and platelet levels, lymphocyte, monocyte, and eosinophil counts. Splenectomy ameliorated inflammation in ITP patients and resulted in a change in percentages of leukocytes in favor of basophils.
Açıklama
Anahtar Kelimeler
Immune thrombocytopenia, Neutrophil-to-lymphocyte ratio, Peripheral blood cells, Splenectomy, Trauma
Kaynak
Cirugia Y Cirujanos
WoS Q Değeri
Q4
Scopus Q Değeri
Q4
Cilt
90
Sayı
2
