TAURINE PREVENTS AGAINST 2,3,7,8-TETRACHLORODIBENZO-P-DIOXIN-INDUCED OXIDATIVE STRESS IN THE LIVER AND KIDNEY OF RATS
Küçük Resim Yok
Tarih
2023
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
University of Ankara
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: The aim of the study was to investigate the preventive effects of taurine against 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced organ damage in rats. The environmental toxin TCDD has a high toxicity in animal and human tissues. Taurine is an amino acid found in many organs, with multiple physiological roles including the protection of cells with its antioxidant and anti-inflammatory properties. In this context, our aim in this study was to investigate the potential preventive effect of taurine on oxidative stress and organ damage caused by TCDD in rat liver and kidney tissues. To evaluate these possible effects, we measured the levels of thiobarbituric acid reactive substances (TBARS), and glutathione (GSH), as well as the activity of superoxide dismutase © 2023 University of Ankara. All rights reserved.
Açıklama
Anahtar Kelimeler
2,3,7,8 tetrachlorodibenzo para dioxin, caspase 3, glutathione, superoxide dismutase, taurine, thiobarbituric acid reactive substance, adult, animal experiment, animal model, animal tissue, Article, blood biochemistry, cell infiltration, controlled study, desquamation, enzyme activity, histopathology, hyperemia, immunohistochemistry, inflammatory cell, kidney hemorrhage, kidney injury, kidney tissue, kidney tubule, liver hemorrhage, liver injury, liver protection, liver tissue, liver toxicity, male, mononuclear cell, nephrotoxicity, nonhuman, oxidative stress, protein expression, rat, renal protection
Kaynak
Ankara Universitesi Eczacilik Fakultesi Dergisi
WoS Q Değeri
Scopus Q Değeri
N/A
Cilt
47
Sayı
2
