Palladium N-Heterocyclic Carbene Pre-catalysts Bearing Different Ancillary Ligands for the Buchwald-Hartwig Amination of Cyclic Secondary Amines with Aryl Chlorides
Küçük Resim Yok
Tarih
2024
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Six novel palladium N-heterocyclic carbene complexes bearing different ancillary ligands such as pyridine, 1-methylimidazole, 4,5-dimethylthiazole and 3-bromoquinoline have been successfully prepared in a one-step process. These complexes were used as pre-catalysts in the Buchwald-Hartwig amination of cyclic secondary amines with aryl chlorides. A range of cyclic secondary amines were tolerated to a wide variety of aryl chlorides in presence of 1 mol% catalyst loading under mild conditions. Under the tested reaction conditions, the expected N-arylamines were obtained in moderate to high yields. The results showed that these novel palladium complexes are effective catalysts for the Buchwald-Hartwig amination.Graphic Abstract
Açıklama
Anahtar Kelimeler
Palladium, N-Heterocyclic carbene, Cyclic secondary amines, Buchwald-Hartwig amination
Kaynak
Catalysis Letters
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
154
Sayı
4
