Effects of goserelin treatment on microvessel density and blood loss associated with transurethral resection of the prostat

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dc.contributor.authorKılıç, Süleyman
dc.contributor.authorKaradag, N.
dc.contributor.authorErgin, H.
dc.contributor.authorAltunoluk, B.
dc.date.accessioned2020-07-16T11:40:58Z
dc.date.available2020-07-16T11:40:58Z
dc.date.issued2014
dc.departmentİnönü Üniversitesien_US
dc.descriptionJournal of Clinical and Analytical Medicine Volume 5, Issue 3, May 2014, Pages 229-233en_US
dc.description.abstractAim: To determine the effects of one dose goserelin before transurethral resection of the prostate (TUR-P) on blood loss and microvessel density (MVD) of prostatic suburethral tissues in the patients with benign prostatic hyperplasia (BPH). Material and Method: The patients who planned to have a TUR-P were randomly divided into two groups. Group-1 consisted of 18 patients who were pretreated with 3,6 mgr subcutaneous injection of goserelin acetate one month before the operation. Group-2 was constructed from 21 patients without goserelin acetate pretreatment. The amount of intraoperative haemorrhage was calculated. Total blood loss, total blood loss/duration of surgery and total blood loss/gram of resected tissue were calculated for each patient. Sections from the prostatic suburethral tissues were examined for microvessel density. Results: Quantitative decreases in Hb were greater in group 1 than in group 2, and mean Hb level was statistically significantly lower in group 1 than in group 2 at the control just after the operation (p=0.028). Although all the differences were statistically insignificant, Hb concentration in irrigation fluid and total blood loss during surgery were higher in the group 1 than in the group 2, contrarily, blood loss by duration of TURP and blood loss by weight of resected prostate tissue were less in the group 1 than in the group 2. The MVD was significantly lower in group 2 than in the group 1. Discussion: Single dose goserelin treatment given for one month is not effective in reducing blood loss during TURP and has not suppressive effects on MVD in prostatic tissues.en_US
dc.identifier.citationKilic, S., Karadag, N., Ergin, H., Altunoluk, B. Effects of goserelin treatment on microvessel density and blood loss associated with transurethral resection of the prostat. (2014). Journal of Clinical and Analytical Medicine.en_US
dc.identifier.doi10.4328/JCAM.1294en_US
dc.identifier.endpage233en_US
dc.identifier.issn1309-0720
dc.identifier.issn1309-2014
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-84900313177en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage229en_US
dc.identifier.trdizinid184352en_US
dc.identifier.urihttps://doi.org/10.4328/JCAM.1294
dc.identifier.urihttps://hdl.handle.net/11616/17017
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/184352
dc.identifier.volume5en_US
dc.identifier.wosWOS:000215562200017en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherJournal of Clinical and Analytical Medicineen_US
dc.relation.ispartofJournal of Clinical and Analytical Medicineen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBenign prostatic hyperplasiaen_US
dc.subjectBlood lossen_US
dc.subjectMicrovessel densityen_US
dc.subjectTransurethral resection of prostateen_US
dc.titleEffects of goserelin treatment on microvessel density and blood loss associated with transurethral resection of the prostaten_US
dc.title.alternativeGoserelin tedavisinin prostati{dotless}n transüretral rezeksiyonu ile i?lişkili kan kaybi{dotless} ve mikrovasküler dansite üzerindeki etkisien_US
dc.typeArticleen_US

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