Use of porcine small intestinal submucosa to reconstruct an ovarian defect
Küçük Resim Yok
Tarih
2009
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Ireland Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: To investigate the feasibility of using porcine small intestinal submucosa (SIS) as a scaffold for repairing ovarian defects. Method: Fourteen female New Zealand rabbits undergoing ovarian resection were randomly allocated to 2 equal groups. The unilateral ovarian defects were, repaired with SIS in group I animals and without SIS in group 2 animals (control). The volumes of the ovaries were calculated and the severity of adhesions was assessed in I animal from each group each month. The ovaries were removed and examined under a microscope. Results: The volumes of the SIS-grafted ovaries were larger than those of the operated ovaries of the control animals (P<0.05). The SIS-grafted ovaries had a lower adhesion score than the operated ovaries of the control group (P<0.001). SIS grafts showed hemorrhage and leukocyte infiltration until the 4th week after surgery, but the ovarian tissue appeared to be well organized from the 12th to the 16th week. At the 28th week, primordial follicles were scattered in the SIS graft. Conclusion: SIS graft could be used for repairing the ovary after surgery. (C) 2009 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.
Açıklama
24th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology -- JUL 06-09, 2008 -- Barcelona, SPAIN
Anahtar Kelimeler
Bioscaffold, Ovarian repair, Primordial follicle, Rabbit ovary, Small intestinal submucosa
Kaynak
International Journal of Gynecology & Obstetrics
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
106
Sayı
3
