Use of porcine small intestinal submucosa to reconstruct an ovarian defect

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dc.authoridTağluk, M. Emin/0000-0001-7789-6376
dc.authoridGül, Mehmet/0000-0002-1374-0783
dc.authoridEşrefoğlu, Mukaddes/0000-0003-3380-1480
dc.authoridAYDIN, Nasuhi/0000-0003-3145-2432
dc.authorwosidTağluk, M. Emin/ABH-1005-2020
dc.authorwosidAydin, Nasuhi E/B-6536-2012
dc.authorwosidGül, Mehmet/ABI-6336-2020
dc.authorwosidEşrefoğlu, Mukaddes/JWA-4590-2024
dc.authorwosidelter, koray/A-5082-2018
dc.authorwosidAYDIN, Nasuhi/O-9043-2016
dc.contributor.authorCelik, Onder
dc.contributor.authorEsrefoglu, Mukaddes
dc.contributor.authorHascalik, Seyma
dc.contributor.authorGul, Mehmet
dc.contributor.authorTagluk, M. Emin
dc.contributor.authorElter, Koray
dc.contributor.authorAydin, Engin
dc.date.accessioned2024-08-04T20:31:17Z
dc.date.available2024-08-04T20:31:17Z
dc.date.issued2009
dc.departmentİnönü Üniversitesien_US
dc.description24th Annual Meeting of the European-Society-of-Human-Reproduction-and-Embryology -- JUL 06-09, 2008 -- Barcelona, SPAINen_US
dc.description.abstractObjective: To investigate the feasibility of using porcine small intestinal submucosa (SIS) as a scaffold for repairing ovarian defects. Method: Fourteen female New Zealand rabbits undergoing ovarian resection were randomly allocated to 2 equal groups. The unilateral ovarian defects were, repaired with SIS in group I animals and without SIS in group 2 animals (control). The volumes of the ovaries were calculated and the severity of adhesions was assessed in I animal from each group each month. The ovaries were removed and examined under a microscope. Results: The volumes of the SIS-grafted ovaries were larger than those of the operated ovaries of the control animals (P<0.05). The SIS-grafted ovaries had a lower adhesion score than the operated ovaries of the control group (P<0.001). SIS grafts showed hemorrhage and leukocyte infiltration until the 4th week after surgery, but the ovarian tissue appeared to be well organized from the 12th to the 16th week. At the 28th week, primordial follicles were scattered in the SIS graft. Conclusion: SIS graft could be used for repairing the ovary after surgery. (C) 2009 International Federation of Gynecology and Obstetrics. Published by Elsevier Ireland Ltd. All rights reserved.en_US
dc.identifier.doi10.1016/j.ijgo.2009.03.058
dc.identifier.endpage222en_US
dc.identifier.issn0020-7292
dc.identifier.issue3en_US
dc.identifier.pmid19589526en_US
dc.identifier.scopus2-s2.0-68349157659en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage218en_US
dc.identifier.urihttps://doi.org/10.1016/j.ijgo.2009.03.058
dc.identifier.urihttps://hdl.handle.net/11616/94851
dc.identifier.volume106en_US
dc.identifier.wosWOS:000269782800009en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Ireland Ltden_US
dc.relation.ispartofInternational Journal of Gynecology & Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBioscaffolden_US
dc.subjectOvarian repairen_US
dc.subjectPrimordial follicleen_US
dc.subjectRabbit ovaryen_US
dc.subjectSmall intestinal submucosaen_US
dc.titleUse of porcine small intestinal submucosa to reconstruct an ovarian defecten_US
dc.typeArticleen_US

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