Cytotoxic effects of orthodontic composites.

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dc.authorscopusid6603091605
dc.authorscopusid36099961800
dc.authorscopusid36138154000
dc.authorscopusid36138467300
dc.authorscopusid6603848689
dc.contributor.authorMalkoc S.
dc.contributor.authorCorekci B.
dc.contributor.authorUlker H.E.
dc.contributor.authorYalçin M.
dc.contributor.authorSengün A.
dc.date.accessioned2024-08-04T20:03:30Z
dc.date.available2024-08-04T20:03:30Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVES: To evaluate the cytotoxic effects of five different light-cured orthodontic bonding composites. Materials and Methods: The orthodontic composites Heliosit Orthodontic (Ivoclar), Transbond XT (3M Unitek), Bisco ORTHO (Bisco), Light Bond (Reliance), and Quick Cure (Reliance) were prepared, and the samples were extracted in 3 mL of BME (Basal Medium Eagle) with 10% newborn calf serum for 24 hours. The L929 cells were plated (25,000 cells/mL) in a 96-well dish and maintained in a humidified incubator for 24 hours at 37 degrees C, 5% CO(2), and 95% air. After 24 hours of incubation of the cells, the incubation medium was replaced by the immersed medium in which the samples were stored. Then, L929 cells were incubated in contact with eluates for 24 hours. The cell mitochondrial activity was evaluated by the methyl tetrazolium (MTT) test. Twelve wells were used for each specimen, and the MTT tests were applied two times. The data were statistically analyzed by one-way analysis of variance (ANOVA) and Tukey HSD tests. RESULTS: Results with L929 fibroblasts demonstrated that except for Transbond XT, freshly prepared composite materials did not reduce vital cell numbers (P > .05) compared with the control group. Our data demonstrate that Transbond XT showed significant cytotoxicity compared with the control group. CONCLUSION: Results indicate that tested orthodontic bonding composites are suitable for clinical application, but that further studies using different test methods are needed for Transbond XT.en_US
dc.identifier.endpage576en_US
dc.identifier.issn1945-7103
dc.identifier.issue4en_US
dc.identifier.pmid20482365en_US
dc.identifier.scopus2-s2.0-77955494739en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage571en_US
dc.identifier.urihttps://hdl.handle.net/11616/91850
dc.identifier.volume80en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofThe Angle orthodontisten_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectresin cementen_US
dc.subjectTransbond XTen_US
dc.subjectanalysis of varianceen_US
dc.subjectanimalen_US
dc.subjectarticleen_US
dc.subjectcell shapeen_US
dc.subjectcell survivalen_US
dc.subjectdental bondingen_US
dc.subjectdrug effecten_US
dc.subjectL cellen_US
dc.subjectmitochondrionen_US
dc.subjectmouseen_US
dc.subjectnonparametric testen_US
dc.subjectorthodontic deviceen_US
dc.subjectAnalysis of Varianceen_US
dc.subjectAnimalsen_US
dc.subjectCell Shapeen_US
dc.subjectCell Survivalen_US
dc.subjectDental Bonding, Light-Cureden_US
dc.subjectL Cells (Cell Line)en_US
dc.subjectMiceen_US
dc.subjectMitochondriaen_US
dc.subjectOrthodontic Bracketsen_US
dc.subjectResin Cementsen_US
dc.subjectStatistics, Nonparametricen_US
dc.titleCytotoxic effects of orthodontic composites.en_US
dc.typeArticleen_US

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