Proton MRS in Behcet s disease with and without neurological findings
Yükleniyor...
Dosyalar
Tarih
2003
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Neuroradiology
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Abstract Our aim was to investigate
whether neurological impairment in
Behc¸et s disease (BD) can be assessed
by means of proton MRS and
whether it can assist in prognosis.
We used single-voxel MRS to measure
metabolites in regions of normal-appearing
pons, basal ganglia
and periventricular white matter
(PWM) in 32 patients with chronic
BD patients with and without neurological
deficits and 29 control
subjects. Patients had significantly
higher N-acetylaspartate (NAA)/
creatine (Cr) and choline (Cho)/Cr
ratios in the basal ganglia than the
controls. The Cho/Cr ratio in the
PWM was also significantly higher
in the patients. MRS enabled clear
discrimination of patients and controls
and also revealed spectral differences
between non-neuro-Behc¸et s
disease and neuro-Behc¸et s disease in
the basal ganglia. MRS can be used
to assess brain involvement in BD
even if structural changes are absent.
Açıklama
Anahtar Kelimeler
Behçet's disease, Brain, Magnetic resonance spectroscopy
Kaynak
Neuroradiology
WoS Q Değeri
Scopus Q Değeri
Cilt
45
Sayı
12
Künye
:Baysal, T. Özışık Karaman, H. I. Karlıdağ, R. Saraç, K. Baysal, Ö. Dusak, A. Hazneci, E. Özcan, A. (2003). Proton MRS in Behcet s disease with and without neurological findings. Neuroradiology, 45(12), 860–864.
