Proton MRS in Behcet s disease with and without neurological findings

dc.contributor.authorBaysal, Tamer
dc.contributor.authorÖzışık Karaman, Handan Işın
dc.contributor.authorKarlıdağ, Rıfat
dc.contributor.authorSaraç, Kaya
dc.contributor.authorBaysal, Özlem
dc.contributor.authorDusak, Abdurrahim
dc.contributor.authorHazneci, Ersoy
dc.contributor.authorÖzcan, Abdulcemal
dc.date.accessioned2017-05-26T07:31:26Z
dc.date.available2017-05-26T07:31:26Z
dc.date.issued2003
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAbstract Our aim was to investigate whether neurological impairment in Behc¸et s disease (BD) can be assessed by means of proton MRS and whether it can assist in prognosis. We used single-voxel MRS to measure metabolites in regions of normal-appearing pons, basal ganglia and periventricular white matter (PWM) in 32 patients with chronic BD patients with and without neurological deficits and 29 control subjects. Patients had significantly higher N-acetylaspartate (NAA)/ creatine (Cr) and choline (Cho)/Cr ratios in the basal ganglia than the controls. The Cho/Cr ratio in the PWM was also significantly higher in the patients. MRS enabled clear discrimination of patients and controls and also revealed spectral differences between non-neuro-Behc¸et s disease and neuro-Behc¸et s disease in the basal ganglia. MRS can be used to assess brain involvement in BD even if structural changes are absent.en_US
dc.identifier.citation:Baysal, T. Özışık Karaman, H. I. Karlıdağ, R. Saraç, K. Baysal, Ö. Dusak, A. Hazneci, E. Özcan, A. (2003). Proton MRS in Behcet s disease with and without neurological findings. Neuroradiology, 45(12), 860–864.en_US
dc.identifier.doi10.1007/s00234-003-1052-7en_US
dc.identifier.endpage864en_US
dc.identifier.issn0028-3940
dc.identifier.issue12en_US
dc.identifier.startpage860en_US
dc.identifier.urihttp://link.springer.com/10.1007/s00234-003-1052-7
dc.identifier.urihttps://hdl.handle.net/11616/6933
dc.identifier.volume45en_US
dc.language.isoenen_US
dc.publisherNeuroradiologyen_US
dc.relation.ispartofNeuroradiologyen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBehçet's diseaseen_US
dc.subjectBrainen_US
dc.subjectMagnetic resonance spectroscopyen_US
dc.titleProton MRS in Behcet s disease with and without neurological findingsen_US
dc.typeArticleen_US

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