Proton MRS in Behcet s disease with and without neurological findings
dc.contributor.author | Baysal, Tamer | |
dc.contributor.author | Özışık Karaman, Handan Işın | |
dc.contributor.author | Karlıdağ, Rıfat | |
dc.contributor.author | Saraç, Kaya | |
dc.contributor.author | Baysal, Özlem | |
dc.contributor.author | Dusak, Abdurrahim | |
dc.contributor.author | Hazneci, Ersoy | |
dc.contributor.author | Özcan, Abdulcemal | |
dc.date.accessioned | 2017-05-26T07:31:26Z | |
dc.date.available | 2017-05-26T07:31:26Z | |
dc.date.issued | 2003 | |
dc.department | İnönü Üniversitesi | en_US |
dc.description.abstract | Abstract Our aim was to investigate whether neurological impairment in Behc¸et s disease (BD) can be assessed by means of proton MRS and whether it can assist in prognosis. We used single-voxel MRS to measure metabolites in regions of normal-appearing pons, basal ganglia and periventricular white matter (PWM) in 32 patients with chronic BD patients with and without neurological deficits and 29 control subjects. Patients had significantly higher N-acetylaspartate (NAA)/ creatine (Cr) and choline (Cho)/Cr ratios in the basal ganglia than the controls. The Cho/Cr ratio in the PWM was also significantly higher in the patients. MRS enabled clear discrimination of patients and controls and also revealed spectral differences between non-neuro-Behc¸et s disease and neuro-Behc¸et s disease in the basal ganglia. MRS can be used to assess brain involvement in BD even if structural changes are absent. | en_US |
dc.identifier.citation | :Baysal, T. Özışık Karaman, H. I. Karlıdağ, R. Saraç, K. Baysal, Ö. Dusak, A. Hazneci, E. Özcan, A. (2003). Proton MRS in Behcet s disease with and without neurological findings. Neuroradiology, 45(12), 860–864. | en_US |
dc.identifier.doi | 10.1007/s00234-003-1052-7 | en_US |
dc.identifier.endpage | 864 | en_US |
dc.identifier.issn | 0028-3940 | |
dc.identifier.issue | 12 | en_US |
dc.identifier.startpage | 860 | en_US |
dc.identifier.uri | http://link.springer.com/10.1007/s00234-003-1052-7 | |
dc.identifier.uri | https://hdl.handle.net/11616/6933 | |
dc.identifier.volume | 45 | en_US |
dc.language.iso | en | en_US |
dc.publisher | Neuroradiology | en_US |
dc.relation.ispartof | Neuroradiology | en_US |
dc.rights | info:eu-repo/semantics/openAccess | en_US |
dc.subject | Behçet's disease | en_US |
dc.subject | Brain | en_US |
dc.subject | Magnetic resonance spectroscopy | en_US |
dc.title | Proton MRS in Behcet s disease with and without neurological findings | en_US |
dc.type | Article | en_US |