Virtual non-enhanced dual-energy computed tomography reconstruction: a candidate to replace true non-enhanced computed tomography scans in the setting of suspected liver alveolar echinococcosis

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dc.authoridKantarci, Mecit/0000-0002-1043-6719
dc.authoridKahraman, Aysegul Sagir/0000-0002-2147-1181
dc.authoridOgul, Hayri/0000-0001-5989-3729
dc.authoridAydin, Sonay/0000-0002-3812-6333
dc.authorwosidKantarci, Mecit/AAL-5940-2021
dc.authorwosidKahraman, Aysegul Sagir/S-1526-2016
dc.contributor.authorKantarci, Mecit
dc.contributor.authorAydin, Sonay
dc.contributor.authorKahraman, Aysegul
dc.contributor.authorOgul, Hayri
dc.contributor.authorIrgul, Baris
dc.contributor.authorLevent, Akin
dc.date.accessioned2024-08-04T20:54:49Z
dc.date.available2024-08-04T20:54:49Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractPURPOSE When a suspected hepatic alveolar echinococcosis (AE) lesion is detected on a contrast enhanced computed tomography (CT) scan, an additional triphasic or non-enhanced CT scan is required to determine the presence of calcification and enhancement. As a result, imaging costs and exposure to ionizing radiation will increase. We can create a non- enhanced series from routine contrast-enhanced images using dual-energy CT (DECT) and virtual non- enhanced (VNE) images. This study's objective is to assess virtual non-enhanced DECT reconstruction as a potential diagnostic tool for hepatic AE. METHODS Triphasic CT scans and a routine dual energy venous phase were acquired using a third-generation DECT system. A commercially available software package was used to generate VNE images. Individual evaluations were conducted by two radiologists. RESULTS The study population consisted of 100 patients (30 AE, 70 other solid liver masses). All AE cases were diagnosed [no false positives/negatives, 95% confidence interval (CI) sensitivity: 91.3%-100%; 95% CI specificity: 95.3%-100%]. Interrater agreement was k: 0.79. In total, 33 (33.00%) of the patients had AE, which was detected using both true non-enhanced (TNE) and VNE images. The mean doselength product of a standard triphasic CT was significantly higher than biphasic dual-energy VNE images. CONCLUSION In terms of diagnostic confidence, VNE images are comparable with actual non-enhanced imaging when evaluating hepatic AE. Further, VNE images could replace TNE images with a substantial radiation dose reduction. Advances in knowledge: hepatic cystic echinococcosis and AE are serious and severe diseases with high fatality rates and a poor prognosis if managed incorrectly, especially AE. Moreover, VNE images produce equal diagnostic confidence to TNE images for assessing liver AE, with a significant reduction in radiation dose.en_US
dc.identifier.doi10.4274/dir.2023.221806
dc.identifier.endpage740en_US
dc.identifier.issn1305-3612
dc.identifier.issue6en_US
dc.identifier.pmid37042415en_US
dc.identifier.scopus2-s2.0-85176413406en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage736en_US
dc.identifier.urihttps://doi.org/10.4274/dir.2023.221806
dc.identifier.urihttps://hdl.handle.net/11616/101669
dc.identifier.volume29en_US
dc.identifier.wosWOS:001132417500001en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Soc Radiologyen_US
dc.relation.ispartofDiagnostic and Interventional Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectDECTen_US
dc.subjectvirtual non-enhanceden_US
dc.subjectalveolar echinococcosisen_US
dc.subjectDLPen_US
dc.subjectradiationen_US
dc.titleVirtual non-enhanced dual-energy computed tomography reconstruction: a candidate to replace true non-enhanced computed tomography scans in the setting of suspected liver alveolar echinococcosisen_US
dc.typeArticleen_US

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