Malignancy In Adrenal Incidentalomas: Are Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Significant?
Küçük Resim Yok
Tarih
2024
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Yuzuncu Yil Universitesi Tip Fakultesi
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The aim of this study was to assess the potential of neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) as diagnostic and prognostic parameters in predicting the malignancy potential of adrenal incidentalomas (AI). A retrospective analysis was conducted using data from a prospectively maintained database, including 66 patients with AI. The patients were categorized into two groups: Group M (malignancies) and Group B (benign conditions). Postoperative pathological evaluation revealed adrenocortical cancer in eight patients (12.1%). No statistically significant differences were found between the groups in terms of NLR [Group M: 2.94 ± 1.78, Group B: 2.51 ± 1.08, p = 0.335] and PLR [Group M: 136.90 (98.7-354.05), Group B: 118.39 (28.5-315.32), p = 0.479]. However, analysis of adrenal mass size revealed a statistically significant difference, with Group M having a mean size of 80.5 mm (range: 40-146) and Group B having a mean size of 60.5 mm (range: 40-122) (p = 0.008). While NLR and PLR showed numerical increases in malignant adrenal masses, their utility in differentiating between benign and malignant masses was not significant. Further investigation of NLR and PLR in larger cohorts of patients with AI is recommended to better understand their diagnostic and prognostic value in this context. © 2024, Yuzuncu Yil Universitesi Tip Fakultesi. All rights reserved.
Açıklama
Anahtar Kelimeler
Adrenal mass, incidentaloma, malignancy, NLR, PLR
Kaynak
Eastern Journal of Medicine
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
29
Sayı
3
