Synthesis and Antimalarial Bioassay of Quinine - Peptide Conjugates

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dc.authoridPanda, Siva/0000-0003-3668-104X
dc.authoridKUCUKBAY, HASAN/0000-0002-7180-9486
dc.authoridSverdrup, Francis/0000-0001-5843-5734
dc.authoridMeyers, Marvin/0000-0001-5484-619X
dc.authorwosidPanda, Siva/E-7856-2014
dc.authorwosidKUCUKBAY, HASAN/A-5050-2019
dc.contributor.authorPanda, Siva S.
dc.contributor.authorIbrahim, Mohamed A.
dc.contributor.authorKucukbay, Hasan
dc.contributor.authorMeyers, Marvin J.
dc.contributor.authorSverdrup, Francis M.
dc.contributor.authorEl-Feky, Said A.
dc.contributor.authorKatritzky, Alan R.
dc.date.accessioned2024-08-04T20:37:51Z
dc.date.available2024-08-04T20:37:51Z
dc.date.issued2013
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAmino acid and peptide conjugates of quinine were synthesized using microwave irradiation in 52-95% yields using benzotriazole methodology. The majority of these conjugates retain in vitro antimalarial activity with IC50 values below 100nm, similar to quinine.en_US
dc.identifier.doi10.1111/cbdd.12134
dc.identifier.endpage366en_US
dc.identifier.issn1747-0277
dc.identifier.issn1747-0285
dc.identifier.issue4en_US
dc.identifier.pmid23497252en_US
dc.identifier.scopus2-s2.0-84884819181en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage361en_US
dc.identifier.urihttps://doi.org/10.1111/cbdd.12134
dc.identifier.urihttps://hdl.handle.net/11616/96220
dc.identifier.volume82en_US
dc.identifier.wosWOS:000324921500001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofChemical Biology & Drug Designen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectamino aciden_US
dc.subjectchemical biologyen_US
dc.subjectdrug designen_US
dc.subjectpeptideen_US
dc.titleSynthesis and Antimalarial Bioassay of Quinine - Peptide Conjugatesen_US
dc.typeArticleen_US

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