Optimal Endoscopic Management of Anastomotic Strictures After DoubleBiliary Reconstruction in Right Lobe Living-Donor Liver Transplantation

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dc.contributor.authorÇağın, Furkan Yasir
dc.contributor.authorErdoğan, Mehmet Ali
dc.contributor.authorSağlam, Osman
dc.contributor.authorYıldırım, Oğuzhan
dc.contributor.authorBilgiç, Yılmaz
dc.contributor.authorArslan, Ahmet Kadir
dc.contributor.authorSarıcı, Kemal Barış
dc.contributor.authorYılmaz, Sezai
dc.date.accessioned2022-02-08T07:41:15Z
dc.date.available2022-02-08T07:41:15Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAbstract: Background: There is no consensus on the optimal drainage technique in the management of biliary anastomotic strictures occurring after right-lobe living-donor liver transplantation (RL LDLT). Aims: To investigate whether there is a superiority between unilateral and bilateral drainage groups in terms of efficacy and safety of biliary drainage in RL LDLT patients undergoing double-biliary reconstruction. Study Design: Retrospective Cohort Methods: Between January 2009 and August 2019, 1693 patients underwent RL LDLT. Of these, 182 patients who developed biliary anastomotic strictures out of the 306 patients who had double-biliary reconstruction, were included in the study. One hundred fifty-five patients with technical success were divided into 2 groups as unilateral (n=116) and bilateral (n=39) drainage groups. The groups were compared in terms of variable parameters such as clinical success, additional procedure, post-ERCP complication, procedures after clinical failure, hospital stay, mortality, and survival. Results: The clinical success was higher in the bilateral group (70% vs. 82%, P = .201). In the initial and the follow-up periods, a total of 44 (38%) patients in the unilateral group were switched to the bilateral drainage group due to the increased need for stenting. The placement of a stent successfully solved the problem only in 28% (32/117) of the patients in the unilateral group, while this rate was 44% (17/39) in the bilateral group. The median follow-up time of both groups was 42 months, and was equal. The number of stent-free follow-up patients in the unilateral drainage group was less than that in the bilateral drainage group (4 and 7, respectively). Conclusion: An active attempt should be made for bilateral drainage in patients with biliary anastomotic stricture following RL LDLT. However, for patients in whom bilateral drainage is not possible, unilateral drainage may be recommended, with the placement of a maximum number of stents following primary biliary balloon dilatation, depending on the degree of stricture.en_US
dc.identifier.citationCAGİN Y. F,ERDOĞAN M. A,SAĞLAM O,YILDIRIM O,BİLGİÇ Y,ARSLAN A. K,SARICI B,YILMAZ S (2021). Optimal Endoscopic Management of Anastomotic Strictures After DoubleBiliary Reconstruction in Right Lobe Living-Donor Liver Transplantation. Balkan Medical Journal, 38(6), 348 - 356. Doi: 10.5152/balkanmedj.2021.21692en_US
dc.identifier.doi10.5152/balkanmedj.2021.21692en_US
dc.identifier.endpage356en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue6en_US
dc.identifier.pmid34860162en_US
dc.identifier.scopus2-s2.0-85119603902en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage348en_US
dc.identifier.trdizinid481774en_US
dc.identifier.urihttps://doi.org/10.5152/balkanmedj.2021.21692
dc.identifier.urihttps://hdl.handle.net/11616/46799
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/481774
dc.identifier.volume38en_US
dc.identifier.wosWOS:000723003700005en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleOptimal Endoscopic Management of Anastomotic Strictures After DoubleBiliary Reconstruction in Right Lobe Living-Donor Liver Transplantationen_US
dc.typeArticleen_US

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