Nomenclature of appendiceal mucinous lesions according to the 2019 WHO Classification of Tumors of the Digestive System

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dc.authoridTurkmen, Samdanci, Emine/0000-0002-0034-5186
dc.authoridAkbulut, Sami/0000-0002-6864-7711
dc.authoridTuncer, Adem/0000-0001-5381-513X
dc.authorwosidKoc, Cemalettin/B-6430-2018
dc.authorwosidTurkmen, Samdanci, Emine/ABH-4716-2020
dc.authorwosidAkbulut, Sami/L-9568-2014
dc.contributor.authorKoc, Cemalettin
dc.contributor.authorAkbulut, Sami
dc.contributor.authorAkatli, Ayse Nur
dc.contributor.authorSamdanci, Emine Turkmen
dc.contributor.authorTuncer, Adem
dc.contributor.authorYilmaz, Sezai
dc.date.accessioned2024-08-04T20:10:01Z
dc.date.available2024-08-04T20:10:01Z
dc.date.issued2020
dc.departmentİnönü Üniversitesien_US
dc.description.abstractBackground/Aims: To analysis the appendiceal mucinous lesions according to the World Health Organization (WHO) 2019 classification of tumors of the digestive system (non-neuroendocrine tumors of the appendix vermiformis) Materials and Methods: Clinical and histopathological data of 37 patients with histopathologically proven appendiceal mucinous lesion from January 2010 to May 2019 were evaluated retrospectively. Pathology slides were re-evaluated by two pathologists according to the WHO 2019 classification of tumors of the digestive system. Results: Totally 37 patients (male:19 female: 18) aged 23 to 93 years were analyzed. Majority of the patients (75.7 %) had underwent appendectomy due to preliminary diagnosis of acute appendicitis (n=22) or periappendiceal tumoral lesions (n=9), the others (n=9) underwent incidental appendectomy. Whereas acute appendicitis was histopathologically diagnosed in 16 (43.2%) patients, perforation was diagnosed in 12 (32.4%) patients (perforation without appendicitis=3, perforation with appendicitis=6). According to the initial, pathology reports were prepared as follows: mucocele (n= 10), mucinous cystadenoma (n=9), low-grade mucinous neoplasm (n=6), mucinous adenocarcinoma (n=5), mucosal hyperplasia (n=5), hyperplastic polyp (n=1), adenomatous polyp (n=1). On the basis of the WHO 2019 classification, pathology reports were prepared as follows: low-grade mucinous neoplasm (n=17), simple retention cysts (n=6), hyperplastic polyp (n=6), mucinous adenocarcinoma (n=5), ruptured appendiceal diverticula (n=2), sessile serrated lesion (n=1). Conclusion: The term of appendiceal mucinous lesion, which is recently introduced into medical literature is suitable to distinguish between lesions with and without malignancy potential. The WHO 2019 classification system has been an important step in simplifying the classification of non- neuroendocrine tumors of the appendix vermiformis.en_US
dc.identifier.doi10.5152/tjg.2020.20537
dc.identifier.endpage657en_US
dc.identifier.issn2148-5607
dc.identifier.issue9en_US
dc.identifier.pmid33090102en_US
dc.identifier.scopus2-s2.0-85094165866en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage649en_US
dc.identifier.trdizinid408456en_US
dc.identifier.urihttps://doi.org/10.5152/tjg.2020.20537
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/408456
dc.identifier.urihttps://hdl.handle.net/11616/92567
dc.identifier.volume31en_US
dc.identifier.wosWOS:000583804200007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAppendectomyen_US
dc.subjectmucoceleen_US
dc.subjectmucinous cystadenomaen_US
dc.subjectmucinous lesionsen_US
dc.titleNomenclature of appendiceal mucinous lesions according to the 2019 WHO Classification of Tumors of the Digestive Systemen_US
dc.typeArticleen_US

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