Liver transplantation in pediatric monogenic metabolic diseases
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Galenos Publ House
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Monogenic diseases are the results of a single gene mutation leading to alterations or defects in a single enzyme causing severe metabolic derangements causing multi -systemic systemic disease and even death Current management strategies include diet to reduce the accumulation of metabolic waste products and treatment to increase the excretion of the toxic metabolites and to induce the activity of the mutant enzyme. However, liver transplantation the only therapeutic strategy that offers a chance of cure to children with certain genetic diseases.
Açıklama
Anahtar Kelimeler
Liver transplantation, pediatric liver diseases, pediatric monogenic diseases
Kaynak
Trends in Pediatrics
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
4
Sayı
4
