Liver Transplantation for Autoimmune Hepatitis: 20 Years of Tertiary Centre Experience

dc.contributor.authorSaglam, Osman
dc.contributor.authorHarputluoglu, Muhsin Murat Muhip
dc.contributor.authorBilgic, Yilmaz
dc.contributor.authorYilmaz, Sezai
dc.contributor.authorYagin, Fatma Hilal
dc.contributor.authorEfe, Cumali
dc.date.accessioned2026-04-04T13:30:45Z
dc.date.available2026-04-04T13:30:45Z
dc.date.issued2025
dc.departmentİnönü Üniversitesi
dc.description.abstractBackground/Aims: We analyzed the frequency of complications and survival rates in patients with autoimmune hepatitis (AIH) who underwent liver transplantation at a high-volume transplant center. Materials and Methods: Patients who underwent transplantation forAIH at the & Idot;n & ouml;n & uuml; University Liver Transplantation Institute between January 2002 and December 2021 were included. Patients with a confirmed diagnosis of AIH, without concomitant chronic liver disease, were included in the study. Results: We included 51 patients (31 female) with a median age of 38.5 years (18-65 years). The 12-month and 60-month survival rates were 86.3% and 80.9%, respectively. During a median 2.22 years follow-up, 9 patients died. Six patients died due to systemic infection, 1 due to biliary complications, and 2 patients due to graft rejection. Autoimmune hepatitis recurrence developed in 6 (11%) patients. Overall, biliary complications developed in 56% (28/51) of patients following liver transplantation, and graft rejection occurred in 22% (11/51) of patients. Conclusion: Our results suggest that the outcome of AIH following liver transplantation is good, with a survival rate of up to 80%. Post- transplant biliary complications are common; therefore, close follow-up is necessary.
dc.identifier.doi10.5152/tjg.2024.24464
dc.identifier.issn2148-5607
dc.identifier.issue3
dc.identifier.orcid0000-0002-9415-147X
dc.identifier.orcid0000-0003-0779-992X
dc.identifier.pmid39696995
dc.identifier.scopus2-s2.0-105000277626
dc.identifier.scopusqualityQ3
dc.identifier.trdizinid1346274
dc.identifier.urihttps://doi.org/10.5152/tjg.2024.24464
dc.identifier.urihttps://search.trdizin.gov.tr/tr/yayin/detay/1346274
dc.identifier.urihttps://hdl.handle.net/11616/108353
dc.identifier.volume36
dc.identifier.wosWOS:001447453000003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.indekslendigikaynakTR-Dizin
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherAves
dc.relation.ispartofTurkish Journal of Gastroenterology
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.snmzKA_WOS_20250329
dc.subjectAutoimmune hepatitis
dc.subjectliver transplantation
dc.subjectpost-transplant complications
dc.titleLiver Transplantation for Autoimmune Hepatitis: 20 Years of Tertiary Centre Experience
dc.typeArticle

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