Effects of reciprocal interactions between various dietary fats and circadian phases on postprandial hyperlipidemia in rats
Yükleniyor...
Dosyalar
Tarih
2018
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
TAYLOR & FRANCIS LTD, 2-4 PARK SQUARE, MILTON PARK, ABINGDON OR14 4RN, OXON, ENGLAND
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Expression levels of various intestinal proteins involved in postprandial lipoprotein assembly as well as plasma triglyceride concentration exhibit daily oscillations indicating circadian control. The length of the carbon chain and degree and position of unsaturation of fatty acids influence triglyceride secretion by the enterocytes. To this end, effects of reciprocal interactions of various single fats/oil (olive oil, fish oil or butter) gavaging either in active or passive phase were investigated in rats. Fat/oil gavaged in the active phase of circadian rhythm resulted in higher postprandial serum triglyceride levels compared to that in the passive phase. Moreover, olive oil led to higher MTP activity and apo B-48 gene expression, while fish oil gavaging caused more prominent apo B-48 and MTP gene expression when they were given in the passive phase. The present results indicate that circadian time at which fat or oil gavaged once might exert influence on postprandial lipoprotein synthesis/assembly.
Açıklama
Anahtar Kelimeler
Apolıpoproteın A-Iv, Nonfastıng Trıglycerıdes, Gene-Expressıon, Secretıon, Clock, Food, Adaptatıon, Metabolısm, Nutrıtıon, Rhythms
Kaynak
Bıologıcal rhythm research
WoS Q Değeri
Scopus Q Değeri
Cilt
49
Sayı
1
Künye
Satılmış, B. Kayhan, B. Güldür, T. (2018). Effects of reciprocal interactions between various dietary fats and circadian phases on postprandial hyperlipidemia in rats. Cilt:49 Sayı:1, 77-91 ss.
