Do the trace elements play a role in the etiopathogenesis of developmental dysplasia of hip?
Küçük Resim Yok
Tarih
2018
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Verducı publısher, vıa gregorıo vıı, rome, 186-00165, ıtaly
Erişim Hakkı
info:eu-repo/semantics/restrictedAccess
Özet
OBJECTIVE: Alterations in the connective tissue of the hip joint capsule and ligaments might account for the increased laxity seen in patients with developmental dysplasia of the hip. The tensile features of the connective tissue depend on collagen. A number of prior studies have noted the association between the trace elements and collagen biosynthesis. The aim of this research is to determine whether there exists an association between the trace elements and developmental dysplasia of the hip.
PATIENTS AND METHODS: This investigation included 27 patients with developmental dysplasia of the hip (18 females and nine males; mean age 24.3 +/- 6.3 months, range 18-36 months) and 26 healthy controls (15 females and 11 males; mean age 23.8 +/- 5.4 months, range 18-36 months). The levels of the serum trace elements in the groups were statistically compared.
RESULTS: The Cu levels of the patients with developmental dysplasia of hip were statistically higher than those of the control group (p<0.05). The Zn, Fe, Mg, and Mn levels of the patients with developmental dysplasia of hip were statistically lower than those of the control group (p<0.05).
CONCLUSIONS: We found an association between developmental dysplasia of the hip and the serum trace element levels. We, therefore, believe that the trace element levels may shed light on the etiopathogenesis of developmental dysplasia of the hip. This work should be supported by future studies concerning the causes of the alterations in the serum trace element levels seen in patients with developmental dysplasia of the hip
Açıklama
Anahtar Kelimeler
Prolıdase actıvıty, connectıve-tıssue, osteoarthrıtıs, cartılage, dıseases, metals
Kaynak
European revıew for medıcal and pharmacologıcal scıences
WoS Q Değeri
Scopus Q Değeri
Cilt
22
Sayı
4
Künye
Guner, S.Guner, SI. Gokalp, MA. Ceylan, MF. Unsal, SS. Demir, H. (2018). Do the trace elements play a role in the etiopathogenesis of developmental dysplasia of hip?. Cilt:22. Sayı:4. 910-913 ss.
