Do the trace elements play a role in the etiopathogenesis of developmental dysplasia of hip?

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dc.contributor.authorGuner, S.
dc.contributor.authorGuner, SI
dc.contributor.authorGokalp, MA
dc.contributor.authorCeylan, MF
dc.contributor.authorUnsal, SS
dc.contributor.authorDemir, H
dc.date.accessioned2019-07-10T08:26:56Z
dc.date.available2019-07-10T08:26:56Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractOBJECTIVE: Alterations in the connective tissue of the hip joint capsule and ligaments might account for the increased laxity seen in patients with developmental dysplasia of the hip. The tensile features of the connective tissue depend on collagen. A number of prior studies have noted the association between the trace elements and collagen biosynthesis. The aim of this research is to determine whether there exists an association between the trace elements and developmental dysplasia of the hip. PATIENTS AND METHODS: This investigation included 27 patients with developmental dysplasia of the hip (18 females and nine males; mean age 24.3 +/- 6.3 months, range 18-36 months) and 26 healthy controls (15 females and 11 males; mean age 23.8 +/- 5.4 months, range 18-36 months). The levels of the serum trace elements in the groups were statistically compared. RESULTS: The Cu levels of the patients with developmental dysplasia of hip were statistically higher than those of the control group (p<0.05). The Zn, Fe, Mg, and Mn levels of the patients with developmental dysplasia of hip were statistically lower than those of the control group (p<0.05). CONCLUSIONS: We found an association between developmental dysplasia of the hip and the serum trace element levels. We, therefore, believe that the trace element levels may shed light on the etiopathogenesis of developmental dysplasia of the hip. This work should be supported by future studies concerning the causes of the alterations in the serum trace element levels seen in patients with developmental dysplasia of the hipen_US
dc.identifier.citationGuner, S.Guner, SI. Gokalp, MA. Ceylan, MF. Unsal, SS. Demir, H. (2018). Do the trace elements play a role in the etiopathogenesis of developmental dysplasia of hip?. Cilt:22. Sayı:4. 910-913 ss.en_US
dc.identifier.endpage913en_US
dc.identifier.issue4en_US
dc.identifier.startpage910en_US
dc.identifier.urihttps://hdl.handle.net/11616/12481
dc.identifier.volume22en_US
dc.language.isoenen_US
dc.publisherVerducı publısher, vıa gregorıo vıı, rome, 186-00165, ıtalyen_US
dc.relation.ispartofEuropean revıew for medıcal and pharmacologıcal scıencesen_US
dc.rightsinfo:eu-repo/semantics/restrictedAccessen_US
dc.subjectProlıdase actıvıtyen_US
dc.subjectconnectıve-tıssueen_US
dc.subjectosteoarthrıtısen_US
dc.subjectcartılageen_US
dc.subjectdıseasesen_US
dc.subjectmetalsen_US
dc.titleDo the trace elements play a role in the etiopathogenesis of developmental dysplasia of hip?en_US
dc.typeArticleen_US

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