Synthesis of new anthraquinone compounds and evaluation of their considerable xanthine oxidase inhibitory activities

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dc.authoridYilmaz, Omer/0000-0002-0962-2725
dc.authoridYilmaz, Ulku/0000-0002-2806-4781
dc.authorwosidYilmaz, Omer/KHZ-8294-2024
dc.authorwosidYilmaz, Ulku/AAA-7545-2020
dc.contributor.authorParladi, Ufuk
dc.contributor.authorYilmaz, Ulku
dc.contributor.authorNoma, Samir Abbas Ali
dc.contributor.authorAtes, Burhan
dc.contributor.authorKucukbay, Hasan
dc.date.accessioned2024-08-04T20:53:37Z
dc.date.available2024-08-04T20:53:37Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractA series of anthraquinone derivatives (1-11) was prepared using alkyl halides, quinizarin, and danthron. The structural analysis of new compounds was carried out by 1H, 13C NMR, IR, and UV-Vis spectroscopic techniques. Xanthine oxidase inhibitory activities of compounds were measured using allopurinol as a standard. Inhibition abilities were identified by measuring the uric acid formation at 294 nm at 37 degrees C. According to the IC50 values of the compounds, it was observed that all the compounds in the group had higher inhibition values than allopurinol.en_US
dc.identifier.doi10.24820/ark.5550190.p011.810
dc.identifier.issn1551-7004
dc.identifier.issn1551-7012
dc.identifier.scopus2-s2.0-85152746666en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.urihttps://doi.org/10.24820/ark.5550190.p011.810
dc.identifier.urihttps://hdl.handle.net/11616/101294
dc.identifier.wosWOS:000891399000001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherArkat Usa Incen_US
dc.relation.ispartofArkivocen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnthraquinone derivativeen_US
dc.subjectquinizarinen_US
dc.subjectdanthronen_US
dc.subjectxanthine oxidaseen_US
dc.subjectinhibitionen_US
dc.titleSynthesis of new anthraquinone compounds and evaluation of their considerable xanthine oxidase inhibitory activitiesen_US
dc.typeArticleen_US

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