A Retrospective Evaluation of Children Diagnosed with Dermatomyositis: A Single-center Study

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dc.authoridKirik, SERKAN/0000-0002-8658-2448
dc.authoridGUNGOR, SERDAL/0000-0003-3875-6770
dc.authoridASLAN, MAHMUT/0000-0002-5355-8994
dc.authorwosidKirik, SERKAN/ADX-1582-2022
dc.contributor.authorAslan, Mahmut
dc.contributor.authorGungor, Serdal
dc.contributor.authorTabel, Yilmaz
dc.contributor.authorOzgor, Bilge
dc.contributor.authorKirik, Serkan
dc.date.accessioned2024-08-04T20:10:12Z
dc.date.available2024-08-04T20:10:12Z
dc.date.issued2022
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Juvenile idiopathic inflammatory myopathies are systemic autoimmune disorders that are characterized by chronic skeletal muscle inflammation, skin rashes and other systemic involvements. We analyzed the clinical findings, laboratory values at admission and treatment protocols and treatment responses of patients who were followed up with a diagnosis of juvenile dermatomyositis (JDM) in a department of pediatric neurology and rheumatology clinics. Methods: Fifteen patients who were referred to the department of pediatric neurology and pediatric rheumatology clinics, diagnosed with JDM between 2010 and 2017 were evaluated retrospectively via their medical records. Results: Of the study sample, 12 (80%) of the patients were female and 3 (20%) were male, and their mean age was 9.26 +/- 3.21 years. The mean time between complaint and diagnosis was 7.8 +/- 6 months, and the patients were followed up for 24.93 +/- 15.28 months after their diagnosis. The mean creatine kinase levels of the patients were 1.354 +/- 840 U/L. Fifteen (100%) of the patients had muscle weakness, 14 (93.3%) had Gottron's papules and 12 (80%) patients had a heliotrope rash. Ten (66.6%) underwent muscle biopsy, 9 (60%) underwent electromyography and 5 (33.3%) patients underwent muscle magnetic resonance imaging. All the patients were treated with corticosteroids and immunosuppressive agents. Conclusion: JDM is a rare inflammatory myopathy observed during childhood. Better responses can be achieved by early diagnosis, intensive immunosuppressive therapy and effective physical therapy.en_US
dc.identifier.doi10.4274/BMJ.galenos.2022.2021.12-9
dc.identifier.endpage171en_US
dc.identifier.issn1305-9319
dc.identifier.issn1305-9327
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85133891492en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage164en_US
dc.identifier.trdizinid1165157en_US
dc.identifier.urihttps://doi.org/10.4274/BMJ.galenos.2022.2021.12-9
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1165157
dc.identifier.urihttps://hdl.handle.net/11616/92657
dc.identifier.volume18en_US
dc.identifier.wosWOS:000825327700009en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofMedical Journal of Bakirkoyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectJuvenile dermatomyositisen_US
dc.subjectsteroiden_US
dc.subjectcreatine kinaseen_US
dc.subjectmuscle biopsyen_US
dc.titleA Retrospective Evaluation of Children Diagnosed with Dermatomyositis: A Single-center Studyen_US
dc.typeArticleen_US

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