EVALUATION OF CASES PRESENTING WITH MYELITIS IN CHILDHOOD

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dc.contributor.authorAslan, Mahmut
dc.contributor.authorGungor, Serdal
dc.date.accessioned2024-08-04T20:10:11Z
dc.date.available2024-08-04T20:10:11Z
dc.date.issued2021
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Myelitis is a monophasic inflammatory demyelinating disease of the spinal cord and brain, often of unknown origin. It is characterized with motor, sensory, and autonomic symptoms. In the childhood age group, it is most frequently seen as acute disseminated encephalomyelitis (ADEM) and transverse myelitis. In this study, the patients who presented to our clinic with myelitis were evaluated. Material and Methods: Patients who were referred to Inonu University Paediatric Neurology Clinic with myelitis between 2012 and 2019 were included in the present study. Our patients' diagnoses, demographic findings, treatments, and treatment responses were evaluated. Results: Thirty-eight patients, 23 with ADEM and 15 with transverse myelitis, were included in the study. The average age of patients was 8.52 +/- 4.19. Seventy-three-point nine percent (73.9%) of the ADEM patients were male, while 46.7% of the transverse myelitis patients were male. The average follow-up time with patients was 22.65 +/- 17.71 months. In terms of therapy, 28 of patients were given steroid, three were given IVIG, six were given steroid+IVIG, and one was given steroid+IVIG+plasmapheresis. Two of patients followed with transverse myelitis were polyphasic, while one was monophasic. Encephalopathy was seen in 82.6% of patients followed with ADEM, while seizure was seen in eight and fever was seen in 19. We had three anti-myelin oligodendrocyteglycoprotein (Anti-MOG) positive patients. One of these patients had optic neuritis attack after transverse myelitis and was diagnosed with neuromyelitis optic spectrum disorder. Conclusion: Myelitis is a significant neurological emergency rarely seen in childhood. The patients should be recognized and treated fast in terms of prognosis. In Anti-MOG positive patients, more care should be taken in treatment and the patients should be followed for a long period of time.en_US
dc.identifier.doi10.26650/IUITFD.2019.0048
dc.identifier.endpage248en_US
dc.identifier.issn1305-6441
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85130394199en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage245en_US
dc.identifier.trdizinid415746en_US
dc.identifier.urihttps://doi.org/10.26650/IUITFD.2019.0048
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/415746
dc.identifier.urihttps://hdl.handle.net/11616/92650
dc.identifier.volume84en_US
dc.identifier.wosWOS:000646763200014en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isotren_US
dc.publisherIstanbul Univ, Fac Medicine, Publ Offen_US
dc.relation.ispartofJournal of Istanbul Faculty of Medicine-Istanbul Tip Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMyelitisen_US
dc.subjectADEMen_US
dc.subjecttransversemyelitisen_US
dc.subjectanti-MOGen_US
dc.titleEVALUATION OF CASES PRESENTING WITH MYELITIS IN CHILDHOODen_US
dc.typeArticleen_US

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