The Antioxidant Effect of Melatonin on Myocardial Ischemia Reperfusion Injury in Experimental Studies
Küçük Resim Yok
Tarih
2014
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Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
A lot of mechanisms play major role in the myocardial ischemia reperfusion injury (MI/R), especially reactive oxygen species (ROS) which they formed rapidly when molecular oxygen enters into the cell. Melatonin, major hormone of the pineal gland, has very strong antioxidant and free radical scavenger effects. Besides, melatonin plays an important role in the regulation of various body functions including circadien sleep rhythms, blood pressure, oncogenesis, retinal function, and immunity. It can be possible to say that oxidative stress occurs during MI/R and melatonin administration exerts an infarct size limiting effect, antiapoptic, antiarryhtmic effects and enhances antioxidant activity of the heart.
Açıklama
Anahtar Kelimeler
Kaynak
Medicine Science
WoS Q Değeri
Scopus Q Değeri
Cilt
3
Sayı
4
