Effect of CPAP on sleep spindles in patients with OSA
Küçük Resim Yok
Tarih
2018
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Science Bv
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: Consequences of OSAS include excessive daytime sleepiness, divided sleep architecture, impaired neurocognitive performance, and significant psychosocial disruption. In this study we aimed to evaluate sleep spindles changes before and after PAP treatment in patient with OSA. Methods: Seventy-three consecutive patients (M/F:61/12) who applied to Sleep Disorders Center of Inonu University Hospital and met the inclusion criteria were enrolled to this study. Full-night polysomnography and CPAP titration were performed. Results: Mean AHI were detected as 43,8 +/- 24,4 and mean oxygen saturation was 79% in patients under full night PSG. Singificant increasing were observed on spindle count under CPAP titration (192 +/- 98.vs 347 +/- 165 per hour p < 0.001)) and also significant increasing was recorded on oxygen saturation (79 15 vs 94 +/- 4% p < 0.001). Conclusion: Both spindle count and oxygen saturation were recorded to be significantly increased under CPAP titration while there was a significant decrease in apnea-hypopnea. We have shown that significant increase in number of spindles can be achieved with CPAP treatment, those to be decreased in patient with OSA. Number of spindles may play a role as an indicator of better outcome in OSA patients.
Açıklama
Anahtar Kelimeler
Sleep apnea obstructive sleep apnea, Sleep spindle, Neurocognitive impairment, CPAP, Intermittent hypoxia
Kaynak
Respiratory Physiology & Neurobiology
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
247
