Effect of CPAP on sleep spindles in patients with OSA

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dc.contributor.authorYetkin, Ozkan
dc.contributor.authorAydogan, Deniz
dc.date.accessioned2024-08-04T20:43:59Z
dc.date.available2024-08-04T20:43:59Z
dc.date.issued2018
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: Consequences of OSAS include excessive daytime sleepiness, divided sleep architecture, impaired neurocognitive performance, and significant psychosocial disruption. In this study we aimed to evaluate sleep spindles changes before and after PAP treatment in patient with OSA. Methods: Seventy-three consecutive patients (M/F:61/12) who applied to Sleep Disorders Center of Inonu University Hospital and met the inclusion criteria were enrolled to this study. Full-night polysomnography and CPAP titration were performed. Results: Mean AHI were detected as 43,8 +/- 24,4 and mean oxygen saturation was 79% in patients under full night PSG. Singificant increasing were observed on spindle count under CPAP titration (192 +/- 98.vs 347 +/- 165 per hour p < 0.001)) and also significant increasing was recorded on oxygen saturation (79 15 vs 94 +/- 4% p < 0.001). Conclusion: Both spindle count and oxygen saturation were recorded to be significantly increased under CPAP titration while there was a significant decrease in apnea-hypopnea. We have shown that significant increase in number of spindles can be achieved with CPAP treatment, those to be decreased in patient with OSA. Number of spindles may play a role as an indicator of better outcome in OSA patients.en_US
dc.identifier.doi10.1016/j.resp.2017.09.008
dc.identifier.endpage73en_US
dc.identifier.issn1569-9048
dc.identifier.issn1878-1519
dc.identifier.pmid28923780en_US
dc.identifier.scopus2-s2.0-85029540577en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage71en_US
dc.identifier.urihttps://doi.org/10.1016/j.resp.2017.09.008
dc.identifier.urihttps://hdl.handle.net/11616/97969
dc.identifier.volume247en_US
dc.identifier.wosWOS:000417963200012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofRespiratory Physiology & Neurobiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSleep apnea obstructive sleep apneaen_US
dc.subjectSleep spindleen_US
dc.subjectNeurocognitive impairmenten_US
dc.subjectCPAPen_US
dc.subjectIntermittent hypoxiaen_US
dc.titleEffect of CPAP on sleep spindles in patients with OSAen_US
dc.typeArticleen_US

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