Plasma malondialdehyde and nitric oxide levels in age related macular degeneration
Küçük Resim Yok
Tarih
2001
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
British Med Journal Publ Group
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Aims-To evaluate alteration of plasma malondialdehyde (MDA) and nitric oxide (NO) levels in patients with exudative age related macular degeneration (ARMD). Methods-Plasma. nitrite plus nitrate concentrations as an index of plasma NO levels and plasma MDA level as a marker of lipid peroxidation were measured in patients with exudative ARMD and age and sex matched healthy subjects. Results-Significantly higher MDA and lower NO levels were detected in plasma of patients with ARMD compared with their controls (p=0.01, p=0.001, respectively). Conclusion-The results may support involvement of oxidative damage and vascular theory in the pathogenesis of ARMD as part of the ageing process.
Açıklama
Anahtar Kelimeler
Ocular Blood-Flow, Retinal Function Recovery, Lipid-Peroxidation, Synthase Inhibition, Antioxidant Enzymes, Resistance, Vitamin, Serum
Kaynak
British Journal of Ophthalmology
WoS Q Değeri
Q2
Scopus Q Değeri
N/A
Cilt
85
Sayı
12
