Plasma malondialdehyde and nitric oxide levels in age related macular degeneration

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dc.authorid, osman/0000-0003-0911-8649;
dc.authorwosid, osman/H-3027-2019
dc.authorwosidUz, Efkan/B-2943-2016
dc.contributor.authorTotan, Y
dc.contributor.authorÇekiç, O
dc.contributor.authorBorazan, M
dc.contributor.authorUz, E
dc.contributor.authorSögüt, S
dc.contributor.authorAkyol, Ö
dc.date.accessioned2024-08-04T20:12:18Z
dc.date.available2024-08-04T20:12:18Z
dc.date.issued2001
dc.departmentİnönü Üniversitesien_US
dc.description.abstractAims-To evaluate alteration of plasma malondialdehyde (MDA) and nitric oxide (NO) levels in patients with exudative age related macular degeneration (ARMD). Methods-Plasma. nitrite plus nitrate concentrations as an index of plasma NO levels and plasma MDA level as a marker of lipid peroxidation were measured in patients with exudative ARMD and age and sex matched healthy subjects. Results-Significantly higher MDA and lower NO levels were detected in plasma of patients with ARMD compared with their controls (p=0.01, p=0.001, respectively). Conclusion-The results may support involvement of oxidative damage and vascular theory in the pathogenesis of ARMD as part of the ageing process.en_US
dc.identifier.doi10.1136/bjo.85.12.1426
dc.identifier.endpage1428en_US
dc.identifier.issn0007-1161
dc.identifier.issue12en_US
dc.identifier.pmid11734513en_US
dc.identifier.scopus2-s2.0-0035670811en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1426en_US
dc.identifier.urihttps://doi.org/10.1136/bjo.85.12.1426
dc.identifier.urihttps://hdl.handle.net/11616/93348
dc.identifier.volume85en_US
dc.identifier.wosWOS:000172605300010en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBritish Med Journal Publ Groupen_US
dc.relation.ispartofBritish Journal of Ophthalmologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectOcular Blood-Flowen_US
dc.subjectRetinal Function Recoveryen_US
dc.subjectLipid-Peroxidationen_US
dc.subjectSynthase Inhibitionen_US
dc.subjectAntioxidant Enzymesen_US
dc.subjectResistanceen_US
dc.subjectVitaminen_US
dc.subjectSerumen_US
dc.titlePlasma malondialdehyde and nitric oxide levels in age related macular degenerationen_US
dc.typeArticleen_US

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