Oral and post-transplantation infectious status in patients with hematopoietic stem cell transplants: A prospective observational study
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Elsevier Science Inc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective. Infectious status may be life threatening in hematopoietic stem cell transplant (HSCT) recipients. The aim of this study was to evaluate the effect of oral status on infectious conditions during the neutropenic phase after HSCT.Study Design. Seventy patients with various hematologic malignancies were involved. Before HSCT, oral and periodontal exami-nation, including the number of teeth and decayed, missing, and filled teeth index (DMFT); visible plaque (%); bleeding on prob-ing (BOP [%]); clinical attachment level; and probing depth (PD) values were collected. Daily blood cultures were collected and analyzed in terms of infection-related parameters, including febrile neutropenia (FN), bacteremia, and C-reactive protein (CRP) during the neutropenic phase of HSCT.Results. Forty-two patients (60%) received autologous and 28 (40%) allogeneic HSCT. In both groups, patients without FN after HSCT had significantly lower DMFT index scores and fewer sites with PD >4 mm (P < .05). However, bacteremia, FN, and CRP were similar in patients with periodontitis compared with non-periodontitis patients (P > .05).Conclusions. The results suggest that periodontal status may not significantly impact the infection-related parameters in patients treated for HSCT. However, DMFT and the prevalence of sites with PD >4 mm may be involved in febrile neutropenia. (Oral Surg Oral Med Oral Pathol Oral Radiol 2023;135:242-248)
Açıklama
Anahtar Kelimeler
Periodontal Treatment, Febrile Neutropenia, Dental-Care, Cancer, Leukemia, Complications, Chemotherapy, Bacteremia, Mucositis, Septicemia
Kaynak
Oral Surgery Oral Medicine Oral Pathology Oral Radiology
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
135
Sayı
2
