Oral and post-transplantation infectious status in patients with hematopoietic stem cell transplants: A prospective observational study

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dc.authoridsabancı, arife/0000-0002-0956-1600
dc.authorwosidsabancı, arife/ABG-9792-2020
dc.contributor.authorSabanci, Arife
dc.contributor.authorKuku, Irfan
dc.date.accessioned2024-08-04T20:53:08Z
dc.date.available2024-08-04T20:53:08Z
dc.date.issued2023
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective. Infectious status may be life threatening in hematopoietic stem cell transplant (HSCT) recipients. The aim of this study was to evaluate the effect of oral status on infectious conditions during the neutropenic phase after HSCT.Study Design. Seventy patients with various hematologic malignancies were involved. Before HSCT, oral and periodontal exami-nation, including the number of teeth and decayed, missing, and filled teeth index (DMFT); visible plaque (%); bleeding on prob-ing (BOP [%]); clinical attachment level; and probing depth (PD) values were collected. Daily blood cultures were collected and analyzed in terms of infection-related parameters, including febrile neutropenia (FN), bacteremia, and C-reactive protein (CRP) during the neutropenic phase of HSCT.Results. Forty-two patients (60%) received autologous and 28 (40%) allogeneic HSCT. In both groups, patients without FN after HSCT had significantly lower DMFT index scores and fewer sites with PD >4 mm (P < .05). However, bacteremia, FN, and CRP were similar in patients with periodontitis compared with non-periodontitis patients (P > .05).Conclusions. The results suggest that periodontal status may not significantly impact the infection-related parameters in patients treated for HSCT. However, DMFT and the prevalence of sites with PD >4 mm may be involved in febrile neutropenia. (Oral Surg Oral Med Oral Pathol Oral Radiol 2023;135:242-248)en_US
dc.identifier.doi10.1016/j.oooo.2022.10.002
dc.identifier.endpage248en_US
dc.identifier.issn2212-4403
dc.identifier.issn2212-4411
dc.identifier.issue2en_US
dc.identifier.pmid36344391en_US
dc.identifier.scopus2-s2.0-85141854363en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage242en_US
dc.identifier.urihttps://doi.org/10.1016/j.oooo.2022.10.002
dc.identifier.urihttps://hdl.handle.net/11616/100989
dc.identifier.volume135en_US
dc.identifier.wosWOS:000992404600001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofOral Surgery Oral Medicine Oral Pathology Oral Radiologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPeriodontal Treatmenten_US
dc.subjectFebrile Neutropeniaen_US
dc.subjectDental-Careen_US
dc.subjectCanceren_US
dc.subjectLeukemiaen_US
dc.subjectComplicationsen_US
dc.subjectChemotherapyen_US
dc.subjectBacteremiaen_US
dc.subjectMucositisen_US
dc.subjectSepticemiaen_US
dc.titleOral and post-transplantation infectious status in patients with hematopoietic stem cell transplants: A prospective observational studyen_US
dc.typeArticleen_US

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