The prevalence of lymphoid follicles and intestinal metaplasia in Helicobacter pylori associated clinically significant gastroduodenal diseases

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dc.authorscopusid6603883869
dc.authorscopusid6602730723
dc.authorscopusid18838208900
dc.authorscopusid59192871700
dc.authorscopusid7004289671
dc.authorscopusid6701920045
dc.authorscopusid6603865122
dc.contributor.authorTaskin V.
dc.contributor.authorGurer I.
dc.contributor.authorSari R.
dc.contributor.authorAydin A.
dc.contributor.authorYildirim B.
dc.contributor.authorAladag M.
dc.contributor.authorHilmioglu F.
dc.date.accessioned2024-08-04T20:01:02Z
dc.date.available2024-08-04T20:01:02Z
dc.date.issued1999
dc.departmentİnönü Üniversitesien_US
dc.description.abstractThis study was designed to investigate the prevalence of lymphoid follicle formation and intestinal metaplasia in patients with Helicobacter pylori (H.pylori) associated clinically significant diseases. Biopsies from the antrum, corpus and fundus of stomach were obtained from 153 patients (non-ulcer dyspepsia, n:110; duodenal ulcer n:23, duodenal ulcer complicated by obstruction, n:20) with histopathologically proven H. pylori infection. All biopsies were examined for lymphoid follicle with germinal center and intestinal metaplasia. Lymphoid follicles were found in 44.5% of non-ulcer disypeptic patients, 70% of duodenal ulcer complicated by obstruction patients and in 47.8% of uncomplicated duodenal ulcer patients. In contrast, 15.5% of non-ulcer disypeptic patients and 20% of complicated duodenal ulcer patients had associated intestinal metaplasia while no intestinal metaplasia was observed in uncomplicated duodenal ulcer patients. Intestinal metaplasia incidence was not statistically different among the different gastroduodenal pathologies (P>0.05). However the incidence of lymphoid follicles was significantly higher in patients with complicated duodenal ulcer (P<0.05). Our results indicate that H.pylori infection in complicated duodenal ulcers are relatively chronic and aggressive compared to H.pylori infection in other gastroduodenal disorders.en_US
dc.identifier.endpage201en_US
dc.identifier.issn1300-4948
dc.identifier.issue3en_US
dc.identifier.scopus2-s2.0-0032723459en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage197en_US
dc.identifier.urihttps://hdl.handle.net/11616/91217
dc.identifier.volume10en_US
dc.indekslendigikaynakScopusen_US
dc.language.isotren_US
dc.publisherTurkish Society of Gastroenterologyen_US
dc.relation.ispartofTurkish Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectH. pylorien_US
dc.subjectIntestinal metaplasiaen_US
dc.subjectLymphoid follicleen_US
dc.titleThe prevalence of lymphoid follicles and intestinal metaplasia in Helicobacter pylori associated clinically significant gastroduodenal diseasesen_US
dc.title.alternativeHelicobacter pylori' ye bagli gelismis cesitli gastroduodenal patolojilerde lenfoid follikul ve intestinal metaplazi gorulme sikligien_US
dc.typeArticleen_US

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