Serum interleukin-6 levels in the differential diagnosis of sepsis and transient tachypnea of newborn

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dc.authorscopusid6601972181
dc.authorscopusid56251081500
dc.authorscopusid24399760400
dc.authorscopusid6602387039
dc.authorscopusid24398958700
dc.authorscopusid26665454300
dc.authorscopusid6603784405
dc.contributor.authorUraş N.
dc.contributor.authorKarada? A.
dc.contributor.authorTonbul A.
dc.contributor.authorMete E.
dc.contributor.authorKara S.
dc.contributor.authorKarabel M.
dc.contributor.authorTatli M.M.
dc.date.accessioned2024-08-04T20:01:12Z
dc.date.available2024-08-04T20:01:12Z
dc.date.issued2010
dc.departmentİnönü Üniversitesien_US
dc.description.abstractObjective: The aim of this study was to evaluate the role of serum interleukin-6 (IL-6) levels in the differentiation of neonatal bacterial sepsis and TTN. Material and Methods: The hospital records of 58 newborn infants with respiratory distress who were above 35 weeks of gestational age were investigated. Patients were divided into two groups. The infection group consisted of patients with proven sepsis and clinical sepsis and the other was the TTN group. Clinical findings and white blood cell count, serum C-reactive protein (CRP), IL-6 levels and the ratio of immature neutrophils to total neutrophils count (I/T) were recorded and compared between the two groups. Results: Serum CRP and IL-6 levels were found higher than the normal limits in both of the groups. However there was no significant difference between them. Duration of respiratory distress was longer and I/T ratio significantly higher in the infection group than the TTN group. The combination of IL-6 and I/T ratio yielded a sensitivity of 80%, a specificity of 48%, a positive predictive value of 44.7%, and a negative predictive value of 80% Conclusion: The I/T ratio and IL-6 may contribute to the early diagnosis of sepsis with respiratory symptoms in newborn infants but IL-6 alone cannot distinguish between TTN and sepsis. © Medical Journal of Trakya University. Published by AVES Publishing. All rights reserved.en_US
dc.identifier.endpage366en_US
dc.identifier.issn1301-3149
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-79952222350en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage363en_US
dc.identifier.trdizinid111524en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/111524
dc.identifier.urihttps://hdl.handle.net/11616/91330
dc.identifier.volume27en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isotren_US
dc.publisherEkin Tibbi Yayinciliken_US
dc.relation.ispartofTrakya Universitesi Tip Fakultesi Dergisien_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectInterleukin 6en_US
dc.subjectNewbornen_US
dc.subjectSepsisen_US
dc.subjectTransient tachypneaen_US
dc.titleSerum interleukin-6 levels in the differential diagnosis of sepsis and transient tachypnea of newbornen_US
dc.title.alternativeYenido?anlarda Sepsis ve Yenido?anın Geçici Takipnesinin Ayırıcı Tanısında Serum İnterlökin-6 Düzeylerien_US
dc.typeArticleen_US

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