Synthesis, Characterization, and Carbonic Anhydrase Inhibitory Properties of Silver(I) Complexes of Benzimidazole Derivatives
| dc.contributor.author | Karataş, Mert Olgun | |
| dc.contributor.author | Ergün, Adem | |
| dc.date.accessioned | 2021-12-29T10:27:42Z | |
| dc.date.available | 2021-12-29T10:27:42Z | |
| dc.date.issued | 2019 | |
| dc.department | İnönü Üniversitesi | en_US |
| dc.description.abstract | Abstract: The antimicrobial properties of silver compounds and biological properties ofbenzimidazole derivatives have been well known for many years. In the present study, in terms oftheir biological potential, six novel silver(I)-N-alkylbenzimidazole derivatives were synthesized inorder to examine their carbonic anhydrase (CA) inhibitory properties. All complexes werecharacterized by the combination of 1H NMR, 13C NMR, mass, FT-IR spectroscopic methods andelemental analyses. The inhibitory properties of all complexes were tested on the esterase activityof human CA I and II (hCA I and hCA II). Acetazolamide was used as a standard. All complexesinhibited the hCA I and hCA II activity in the range of 27.37-29.58 µM and 20.93-27.25 µM,respectively. | en_US |
| dc.identifier.citation | KARATAŞ M. O,ERGÜN A (2019). Synthesis, Characterization, and Carbonic Anhydrase Inhibitory Properties of Silver(I) Complexes of Benzimidazole Derivatives. Journal of the Turkish Chemical Society, Section A: Chemistry, 6(2), 253 - 260. Doi: 10.18596/jotcsa.546960 | en_US |
| dc.identifier.doi | 10.18596/jotcsa.546960 | en_US |
| dc.identifier.endpage | 260 | en_US |
| dc.identifier.issn | 2149-0120 | |
| dc.identifier.issue | 2 | en_US |
| dc.identifier.scopus | 2-s2.0-85070517421 | en_US |
| dc.identifier.scopusquality | N/A | en_US |
| dc.identifier.startpage | 253 | en_US |
| dc.identifier.trdizinid | 396234 | en_US |
| dc.identifier.uri | https://doi.org/10.18596/jotcsa.546960 | |
| dc.identifier.uri | https://hdl.handle.net/11616/44675 | |
| dc.identifier.uri | https://search.trdizin.gov.tr/yayin/detay/396234 | |
| dc.identifier.volume | 6 | en_US |
| dc.indekslendigikaynak | TR-Dizin | en_US |
| dc.indekslendigikaynak | Scopus | en_US |
| dc.language.iso | en | en_US |
| dc.relation.ispartof | Journal of the Turkish Chemical Society, Section A: Chemistry | en_US |
| dc.relation.publicationcategory | Makale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı | en_US |
| dc.rights | info:eu-repo/semantics/openAccess | en_US |
| dc.title | Synthesis, Characterization, and Carbonic Anhydrase Inhibitory Properties of Silver(I) Complexes of Benzimidazole Derivatives | en_US |
| dc.type | Article | en_US |
